Handbook of Stable Strontium

ISBN-13: 9781468437003 / Angielski / Miękka / 2012 / 644 str.

Stanley Skoryna

Opis

Nearly two hundred years ago Crawford and Cruickshank, surgeons and chemists in the Royal Artillery, reported the occurrence of a "new earth" in the mines at the Scottish village of Strontian. Humphrey Davy, following the advice of Berzelius, isolated stable strontium in 1808 along with other alkali earth metals. It was not until 1883 that physiological effects of stable strontium were first recognized by none other than Sidney Ringer in his experiments on frog heart. The medicinal use of strontium salts was first described in Squire's Companion in 1894. Subsequently, strontium was introduced into the Pharma copeias of Great Britain, United States, France, Germany, Spain, Italy, and Mexico and was used in treatment of a variety of disease. s, clearly without detailed knowledge of its actions. It is hoped that this handbook will provide a sound basis for further research on stable strontium and the establishment of the levels of intake, necessary or desirable, in different pathophysiological conditions. The objective of this publication was to assemble a comprehensive collection of essays on stable strontium which review the respective areas of research as well as present original data. I consider myself fortunate to have been able to work with the contributors of these essays. It is obvious that this type of book should be interdisciplinary in nature owing to the necessity of examining each subject from the viewpoint of different disciplines."

Spis treści

1 Early History of Strontium.- 2 Chemistry of Strontium.- 3 Biogeochemistry of Strontium.- 4 Skeletogenesis in Scleractinian Corals: The Transport and Deposition of Strontium and Calcium.- 5 Uptake of Stable Strontium by Plants and Effects on Plant Growth.- 6 Interactions of Divalent Cations Affecting Polyribosomal Profiles from Paramecium—With Particular Reference to the Interactions of Strontium with Calcium, Magnesium, and Manganese.- 7 Divalent Cation-Dependent Deposits in Paramecium.- 8 Effect of Strontium Ion on the Hydrolysis of ATP.- 9 The Calcium-Activated Photoprotein Obelin—Effects of Calcium and Strontium and Its Use in the Measurement of Intracellular Ionized Calcium.- 10 Strontium Ions and Membranes: Screening versus Binding at Charged Surfaces.- 11 Transmembrane Strontium Movements and Strontium-Induced Changes in Membrane Cation Permeability in Nonexcitable Cell Membranes.- 12 Mitochondrial Granules in the Liver of Rats Kept on Stable Strontium Supplementation.- 13 Strontium and Animal Mitochondria: The Interaction of Strontium Ions with Mitochondria in Animal Tissues.- 14 Divalent Cations and Regulation of Cyclic Nucleotides in Nervous Systems.- 15 Divalent Metal Ions and the Regulation of Pyruvate Dehydrogenase.- 16 The Relationship between Strontium and Other Divalent Cations in the Process of Transmitter Release from Cholinergic Nerve Endings.- 17 Contractions of Skeletal Muscles and Underlying Changes: Effects of Strontium.- 18 Strontium as the Substitute for Calcium in the Excitation-Contraction Coupling of Crayfish Muscle Fibers.- 19 Effects of Strontium and Some Other Divalent Cations on Electrical and Mechanical Activity in Rat’s Portal Vein.- 20 Effects of Strontium as Substitute for Extracellular Calcium on Contraction and Relaxation of Vascular Smooth Muscle.- 21 Hemodynamic Effects of Strontium in the Dog.- 22 Effects of Strontium Ions on Contractility of Isolated Heart Preparations.- 23 Some Mechanical Characteristics of Strontium-Mediated Contractions in Heart Muscle.- 24 Calcium and Other Divalent Cations as Charge Carriers of the Slow Inward Current in Heart Muscle.- 25 Effects of Calcium, Magnesium, and Strontium on Drug-Receptor Interactions.- 26 Strontium and Histamine Secretion.- 27 Strontium and Platelet Function.- 28 The Effects of Strontium and Calcium on Mammalian Collagenases.- 29 Inhibition of Dihydrostreptomycin Action against Mycobacterium smegmatis by Sodium, Magnesium, and Strontium Salts.- 30 Content of Stable Strontium in Man and Animal Biota.- 31 Effects of Stable Strontium Administration on Calcium Metabolism with Particular Reference to Low-Calcium Diet.- 32 Strontium Metabolism and Mechanism of Interaction with Mineralized Tissues.- 33 Effects of Stable Strontium in Treatment of Osteoporosis.- 34 Strontium in Human Dental Enamel.- 35 Effects of Stable Strontium Supplementation.- Author Index.