Handbook of Nutraceuticals Volume II: Scale-Up, Processing and Automation

ISBN-13: 9781439823682 / Angielski / Twarda / 2011 / 593 str.

Yashwant Vishnupant Pathak

Opis

Due in part to an absence of universally accepted standardization methods, nutraceuticals and functional foods face regulatory ignorance, marketing incompetence and ethical impunity. Even though many researchers believe that there is a connection between nutraceuticals and functional foods and reduced health care expenses as well as disease prevention, the credibility and quality control challenge remains. The industry needs more standardized testing, reliable reproducible clinical studies to prove the efficacies of products in vivo, and in-process controls to maintain universal product quality. The first volume of the Handbook of Nutraceuticals re-defined Nutraceuticals, covering the regulatory aspect as well as insisting on the cGMP's and SOP's for the nutraceutical manufacturing. This second volume focuses on the scale up, processing, and automation of nutraceutical production under cGMP production regulations. It covers: * Advancements in extraction methods * Unit operations involved in scaling up and processing * Rheological and flow properties of products as characterization parameters * Fortification and value enhancement using nanotechnology * Green concepts in food industry * Flavoring of nutraceuticals * Clinical batch nutraceutical manufacturing * New technologies to prevent counterfeiting * Automation in nutraceutical industry The nutraceutical market is at the crossroads. With a nearly $200 billion market for nutraceuticals and functional foods by end of 2013, and promising developments in product design and discovery, the industry must be ready for intense scrutiny. The standardization of testing, clinical studies, and adherence to rigorous industry and scientific methods is necessary for the advancement, acceptance, and development of high quality, effective nutraceuticals. With contributions from leading authorities, this book brings together hundreds of years of combined experience to provide guidance on how to in

Spis treści

Emerging technologies in nutraceutical processing. Challenges in Scaling up nutraceuticals. Microfluidics in nutraceutical processing. Supercritical Fluid in nutraceutical processing. Microencapsulation in nutraceutical processing. Nanotechnology in nutraceutical processing. Converting Liquid products to Solids in nutraceutical processing: Phase transfer processing. cGMP's and other compliance requirements for nutraceutical processing. Worldwide performance standards for nutraceutical processing. Global regulatory trends in Unit operations, Scaling up, processing and automation. Unit operations, Scaling up, processing and automation. Modeling in scaling up and processing. Computer simulations :Automation possibilities in the field of scaling up and processing in nutraceutical processing. Homogenization in nutraceutical processing. Pelletization/Extrusion in nutraceutical processing. Continuous processing vs batch processing in Nutraceutical Processing. Fortification and value enhancement during nutraceutical processing. Sterile nutraceutical processing. Extraction/Fractionation/Purification/Modification of bio- based products in nutraceutical processing. Beyond traditional approach: value addition during nutraceutical processing.Value addition through processing: microencapsulation of existing nutraceuticals and applying nanotechnology in nutraceutical processing.

O autorze

Yashwant Pathak, PhD, Department of Pharmaceutical Sciences, Sullivan University College of Pharmacy, Louisville, Kentucky, USA