Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology

ISBN-13: 9781617370175 / Angielski / Miękka / 2010 / 470 str.

David I. Mostofsky; Shlomo Yehuda

Opis

Internationally eminent scientists illuminate the most important scientific aspects of essential fatty acids (EFAs)-from their biochemistry to their physiological consequences in both health and illness. The distinguished contributors integrate a wide range of topics, including the basic biochemistry of EFAs and lipid metabolism, the role of EFAs in the neuronal membrane, the effects of EFAs and lipids in various diseases, and the effects of normal levels and EFA deficiencies on cognition and behavior. The book's consolidation of our knowledge of the biology and metabolism of the EFAs lays the groundwork for dramatic advances in our understanding of these ubiquitous biochemicals and their role in health and illness.

Spis treści

Part I: Biochemical Properties. Permeability of the Blood-Brain Barrier to Circulating Free Fatty Acids, William A. Banks, Abba J. Kastin, and Stanley I. Rapoport. Fatty Acid Metabolism in Brain in Relation to Development, Membrane Structure, and Signaling, M. Thomas Clandinin and Jacqueline Jumpsen. Abnormalities in Essential Fatty Acid Status in Alcoholism, Norman Salem, Jr. and Nils Urban Olsson. The Biological Properties of Oleic Acid, Elliot M. Berry. n-3 Polyunsaturated Fatty Acids and Human Cytokine Synthesis, Gunther Hartmann and Stefan Endres. Fatty Acid Regulation of Endocrine Activity, Eric P. Widmaier. Part II: Physiology and Health. w3 and w6 Essential Fatty Acid Status in Human Health and Disease, Ralph T. Holman. Visual Function and the Essentiality of a-Linolenic Acid and Docosahexaenoic Acid in Human Infants, Eileen E. Birch, David Birch, and Ricardo Uauy. Neural Function Following Dietary n-3 Fatty Acid Depletion, Andrew J. Sinclair, Harrison S. Weisinger, and Algis J. Vingrys. Polyunsaturated Fats and Learning: Old Data, New Questions, Donald V. Coscina. Fatty Acids, Phospholipids, and Schizophrenia, David F. Horrobin. The Seizing Brain: Phospholipolysis, Oxygen Delivery, and Electrical Activity, Francesco Visioli. Arachidonic Acid, Neurotrauma, and Neurodegenerative Diseases, Akhlaq A. Farooqui, Thad A. Rosenberger, and Lloyd A. Horrocks. Part III: Learning, Cognition, and Complex Behavior. Essential Fatty Acids and Behavior: Is There a Role for the Eicosanoids? Patricia E. Wainwright. Oral and Postingestive Controls of Fat Intake, Danielle Greenberg and Gerard P. Smith. Physiological Role of Fatty Acids in Infancy: Effect of Dietary Fat on Brain Fatty Acids and Learning Ability in Infancy, Akie Yonekubo. Omega-3 Fatty Acid Deficiency and Behavior: A Critical Review and Directions for Future Research, Sydney Reisbick and Martha Neuringer. Effects of Essential Fatty Acid Preparation (SR-3) on Brain Lipids, Biochemistry, and Behavioral and Cognitive Functions, Shlomo Yehuda, Sharon Rabinovitz, and David I. Mostofsky. Index.

Blurb

In Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology, internationally eminent scientists illuminate the most important scientific aspects of essential fatty acids (EFAs)-from their biochemistry to their physiological consequences in both health and illness. The distinguished contributors integrate a wide range of topics, including the basic biochemistry of EFAs and lipid metabolism, the role of EFAs in the neuronal membrane, the effects of EFAs and lipids in various diseases, and the effects of normal levels and EFA deficiencies on cognition and behavior.

The Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology provides the most comprehensive survey available of our knowledge of the biology and metabolism of fatty acids. It brings together diverse areas of biochemistry, behavior, and nutrition, and lays the groundwork for dramatic advances in our understanding of these ubiquitous biochemicals and their role in health and disease.