Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques

ISBN-13: 9780849333293 / Angielski / Twarda / 2007 / 1596 str.

James P. Landers; Landers P. Landers; James P. Landers

Opis

Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application in numerous fields, many scientists still debate its merits. While the body of international CE literature continues to expand dramatically, experts still question whether it has provided the speed, resolving power, peak capacity, sensitivity, robustness, and cost-reduction promised by its pioneers. Responding to these criticisms, this third edition brings together cutting-edge researchers to demonstrate the utility of CE across a broad spectrum of disciplines including

Forensic science

Medical diagnostics

Pharmaceutical science

Genetic analysis

Biotechnology

Fluid mechanics

Environmental science

Biomedical research

Nanotechnology

Proteomics

Detailed Analysis of New Methodologies and Applications Eagerly awaited by researchers and technicians who transformed the first two editions into bestsellers, this latest volume once again delivers. Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Aided by contributions from leading international experts, this text remains a seminal reference for numerous chemistry, biology, and engineering fields."

Spis treści

Fundamentals and Methodologies
Introduction to Capillary Electrophoresis
Protein Analysis by Capillary Electrophoresis
Micellar Electrokinetic Chromatography
Capillary Electrophoresis for Pharmaceutical Analysis
Principles and Practice of Capillary Electrochromatography
Capillary Electrophoresis of Nucleic Acids
Analysis of Carbohydrates by Capillary Electrophoresis
The Coupling of Capillary Electrophoresis and Mass Spectrometry in
Proteomics
Light-Based Detection Methods for Capillary Electrophoresis
Microfluidic Devices for Electrophoretic Separations: Fabrication and Use
Capillary-Based Systems: Core Methods and Technologies
Kinetic Capillary Electrophoresis
DNA Sequencing and Genotyping by Free-Solution Conjugate Electrophoresis
Online Sample Preconcentration for Capillary Electrophoresis
Capillary Electrophoresis for the Analysis of Single Cells: Sampling,
Detection, and Applications
Ultrafast Electrophoretic Separations
DNA Sequencing by Capillary Electrophoresis
Dynamic Computer Simulation Software for Capillary Electrophoresis
Heat Production and Dissipation in Capillary Electrophoresis
Isoelectric Focusing in Capillary Systems
Capillary-Based Systems: Specialized Methods and Technologies
Subcellular Analysis by Capillary Electrophoresis
Chemical Cytometry: Capillary Electrophoresis Analysis at the Level of the Single Cell
Glycoprotein Analysis by Capillary Electrophoresis
Capillary Electrophoresis of Post-Translationally Modified Proteins and Peptides
Extreme Resolution in Capillary Electrophoresis: UHVCE, FCCE, and SCCE
Separation of DNA for Forensic Applications Using Capillary Electrophoresis
Clinical Application of CE
Solid-Phase Microextraction and Solid-Phase Extraction with Capillary Electrophoresis and Related Techniques
CE-SELEX: Isolating Aptamers Using Capillary Electrophoresis
Microfluidic Technology as a Platform to Investigate the Microcirculation
Capillary Electrophoresis Applications for Food Analysis
Separation Strategies for Environmental Analysis
Microchip-Based: Core Methods and Technologies
Cell Manipulation at the Micron Scale
Multidimensional Microfluidic Systems for Protein and Peptide Separations
Microchip Immunoassays
Solvent Extraction on Chips
Electrophoretic Microdevices for Clinical Diagnostics
Advances in Microfluidics: Development of a Forensic Integrated DNA Microchip (IDChip)
Taylor Dispersion in Sample Preconcentration Methods
The Mechanical Behavior of Films and Interfaces in Microfluidic Devices: Implications for Performance and Reliability
Practical Fluid Control Strategies for Microfluidic Devices
Low-Cost Technologies for Microfluidic Applications
Microfluidic Reactors for Small Molecule and Nanomaterial Synthesis
Microchip-Based: Specialized Methods and Technologies
Sample Processing with Integrated Microfluidic Systems
Cell and Particle Separation and Manipulation Using Acoustic Standing Waves in Microfluidic Systems
Optical Detection Systems for Microchips
Microfabricated Electrophoresis Devices for High-Throughput Genetic Analysis: Milestones and Challenges
Macroporous Monoliths for Chromatographic Separations in Microchannels
Microdialysis and Microchip Systems
Microfluidic Sample Preparation for Proteomics Analysis Using MALDI-MS
Implementing Sample Preconcentration in Microfluidic Devices
Using Phase-Changing Sacrificial Materials to Fabricate Microdevices for Chemical Analysis
Materials and Modification Strategies for Electrophoresis Microchips
Microfluidic Devices with Mass Spectrometry Detection
Nanoscale Self-Assembly of Stationary Phases for Capillary Electrophoresis of DNA
Nanoscale DNA Analysis
Index

O autorze

James P. Landers