G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis: Volume 114

ISBN-13: 9780123869333 / Angielski / Twarda / 2013 / 400 str.

Ya-Xiong Tao

Opis

Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.

• Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs
• Chapters are written by leading experts

Recenzje

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Spis treści

G Protein-coupled receptors in energy homeostasis and obesity: An introduction

Y. Tao

Ghrelin receptor in energy homeostasis and obesity pathogenesis

W. Zhang

Obestatin receptor in energy homeostasis and obesity pathogenesis

J. Zhang

Melanocortin-3 receptor in energy homeostasis and obesity pathogenesis

A. Butler

Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis

A. Hinney

G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis

H. Shi

Relaxin-3 receptor in energy homeostasis and obesity pathogenesis

C. Liu

Cholecystokinin receptor in energy homeostasis and obesity pathogenesis

A. Sayegh

Adiponectin receptor in energy homeostasis and obesity pathogenesis.

B. Akingbemi

O autorze

Dr. Ya-Xiong Tao is currently Professor of Physiology at Auburn University College of Veterinary Medicine in Auburn, Alabama, USA. He has been working on several G protein-coupled receptors, including gonadotropin receptors regulating reproduction, and melanocortin receptors regulating energy and glucose homeostasis. He has published extensively in peer-reviewed biomedical journals and obtained funding for his research from National Institutes of Health, American Diabetes Association and American Heart Association, among others. He has delivered numerous lectures at universities and research institutes in USA, Canada, China, India, and Mexico. He has edited ten volumes, including seven volumes in Progress in Molecular Biology and Translational Science. He teaches several courses, including Physiology, Receptorology, Genomics and Personalized Medicine, and Molecular Endocrinology, for veterinarian, graduate, and undergraduate Honors students.