Fundamentals of Toxicology: Essential Concepts and Applications

ISBN-13: 9780128054260 / Angielski / Miękka / 2016 / 422 str.

PK Gupta

Opis

Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.

• Explains the essential concepts of toxicology in a clear fashion
• Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology
• Explores the history, foundations, and most recent concepts of toxicology
• Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Spis treści

Unit I

Chapter 1. Introduction and historical background

Chapter 2. Definitions and scope of toxicology

Chapter 3. Classification of poisons/toxicants

Chapter 4. Factors affecting toxicity

Chapter 5. Natural laws concerning toxicology

Chapter 6. Hazard and risk assessment

Unit II

Chapter 7. Absorption, distribution, and excretion of toxicants

Chapter 8. Biotransformation

Chapter 9. Principles and basic concepts of toxicokinetics

Unit III

Chapter 10. Toxicological testing: Genesis

Chapter 11. Toxicological testing: In vitro models

Chapter 12. Toxicological testing: In vivo systems

Chapter 13. Genotoxicity

Chapter 14. Preclinical toxicological investigations of pharmaceutical products

Chapter 15. Preclinical safety evaluation of biotechnology-derived products

Chapter 16. Preclinical regulatory toxicology for biomaterials and medical devices

Unit IV

Chapter 17. Toxic effects of pesticides (agrochemicals)

Chapter 18. Toxic effects of metals

Chapter 19. Toxic effects of nonmetallics

Chapter 20. Neurotoxic agents

Chapter 21. Toxic effects of cardiac poisons

Chapter 22. Toxic effects of asphyxiants

Chapter 23. Toxic effects of caustics (corrosives)

Chapter 24. Drug toxicity, dependence, and abuse

Chapter 25. Toxic effects of domestic chemicals

Chapter 26. Toxic effects of poisonous plants

Chapter 27. Poisonous foods and food poisoning

Chapter 28. Poisons of animal origin

Chapter 29. Chemical food poisoning

Chapter 30. Health effects of radioactive materials

Unit V

Chapter 31. Basic concepts of forensic toxicology

Chapter 32. Applications in toxicology

Chapter 33. Clinical toxicology

Chapter 34. Treatment of poisoning

O autorze

Prof. Dr. Gupta, Hon DSc, PGDCA, FACVT (USA), FAEB, FST, FASc AW, FNAVSc is an internationally known toxicologist having 48 years of experience in the field of teaching, research and research management. He has guided many post-graduate students for their thesis work in toxicology and was honored with several National and International Awards including best teachers, best researcher, Alarsin award, Lifetime achievements, and IUTOX-Astra Zeneca Award (USA). To his credit he has several books, book chapters (Elsevier, Academic Press, John Wiley, Merck Manual etc) as well as scientific research publications (550) published in National and International peer reviewed Journals of repute. His contribution in the publication of Indian Veterinary Pharmacopeia is highly praise worthy. He is the founder Editor-in-Chief of a peer reviewed scientific journal "Toxicology International”, and Book Review Editor, Marcel Dekker, USA; Expert member Consultant and Advisor to WHO, Geneva; Consultant United Nations FAO, Rome; IAEA, Vienna; Founder Academy of Sciences for Animal Welfare; Founder and Past President, Society of Toxicology of India; Adjunct Professor, SRMS; founder director and member nominating committee of International Union of Toxicology; founder President of Society of Toxicology of India, and has held several prominent positions of scientific organizations in India and abroad.

In addition to this Dr Gupta has also been biographer in several WHO's WHO from all over the world including Marquis WHOs WHO (USA), IBC (UK) and other leading publications of the World. .At present Dr Gupta is a Director of Toxicology Consultant Group, Patron and Founder President of the Society of Toxicology of India, and President of the Academy of Sciences for Animal Welfare.