Folic Acid and Folates: Volume 79

ISBN-13: 9780123742322 / Angielski / Twarda / 2008 / 443 str.

Gerald Litwack

Opis

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.

*Includes color illustrations
*Available on ScienceDirect
*Longest running series published by Academic Press
*Contributions by leading international authorities

Spis treści

1. Folate-Mediated One-Carbon MetabolismJennifer T. Fox and Patrick J. Stover2. Mathematical Models of Folate-Mediated One-Carbon Metabolism H. Frederik Nijhout, Michael C. Reed and C.M. Ulrich3. Folate Deprivation, the Methionine Cycle and Alzheimer¡¦s DiseaseFlaubert Tchantchou and Thomas B. Shea4. Benefits and Risks of Folic Acid Supplementation Young-In Kim5. Molecular Mechanisms of Adaptation to Folate DeficiencyIlan Ifergan and Yehuda G. Assaraf6. Structure and Function of the Reduced Folate Carrier: A Paradigm of a Major Facilitator Superfamily Mammalian Nutrient TransporterLarry H. Matherly and Zhanjun Hou 7. Renal Conservation of Folates: Role of Folate Transport ProteinsVijaya L. Damaraju, Carol E. Cass and Michael B. Sawyer8. Exploitation of the Folate Receptor in the Management of Cancer and Inflammatory DiseaseChristopher P. Leamon and Ann L. Jackman9. Folate Receptor Expression in Pituitary Adenomas: Cellular and Molecular Analysis Chheng-Orn Evans, Congjun Yao, David Leborde and Nelson M. Oyesiku10. Regulation of Human Dihydrofolate Reductase Activity and ExpressionEmine Ercikan Abali, Nancy E. Skacel, Hilal Celikkaya, Yi-Ching Hsieh11. Catalysis of Methyl Group Transfers Involving Tetrahydrofolate and B12Stephen W. Ragsdale12. Methyltetrahydrofolate in Folate-Binding Protein Glycine N-MethyltransferaseZigmund Luka13. Mechanism-Based Inhibitors of Folylpoly-f×-glutamate Synthetase and f×-Glutamyl Hydrolase: Control of Folylpoly-f×-glutamate Homeostasis as a Drug TargetJames K. Coward and John J. McGuire14. Methylenetetrahydrofolate Reductase, Common Polymorphisms and Relation to DiseasePhilip Thomas and Michael Fenech15. Mitochondrial Methylenetetrahydrofolate Dehydrogenase, Methenyltetrahydrofolate Cyclohydrolase and Formyltetrahydrofolate SynthetasesKaren E. Christensen and Robert E. MacKenzie16. The Structure and Mechanism of 6-Hydroxymethyl-7,8-dihydropterin PyrophosphokinaseJeremy P. Derrick

O autorze

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)