Fluoromethylation Reactions

ISBN-13: 9783639169508 / Angielski / Miękka / 2009 / 212 str.

Sujith Chacko

Opis

Fluorocarbon molecules possess unique properties thatmake them useful in various facets of life. Morerecently fluorine chemistry has had a major impact onthe pharmaceutical industry and biomedicinalresearch. The importance of fluorinated molecules andfluorinated analogues of natural compounds is ofgrowing interest to the scientific community becauseof the increased understanding of the importance offluorine in pharmacological properties. It hastriggered the need for developing new syntheticmethodologies for the introduction of fluorine andfluoroalkyl groups into various organic moleculeswhich will enable the scientific world to explore newfluoroorganics. This book covers novel nucleophilicmonofluoromethylation reactions, synthesis of newelectrophilic difluoromethylating reagents and theiruse in making novel difluoro methyl compounds. Thebook also details on the use of solid hydrogenperoxide reagents for ipso hydroxylation of arylboronic acids as well as on the synthesis ofmonodisperse poly vinyl pyridine nanospheres byemulsifier free emulsion polymerization.

O autorze

Dr. Chacko received his Ph.D. in chemistry at University of
Southern California in 2008 under the guidance of Professor G. K.
Surya Prakash and Nobel Laureate Professor George A. Olah. Since
2008, he has been a research chemist at Avery Dennison Cooperation.