Floating Drug Delivery System

ISBN-13: 9783848425280 / Angielski / Miękka / 156 str.

Basavaraj Nanjwade; Sagar A. Adichwal

Opis

Floating drug delivery system or hydrodynamically balance systems have a bulk density lower than gastric fluid and thus remains buoyant in the stomach for a prolonged period of time without affecting the gastric emptying rate. While the system is floating on gastric contents the drug is released slowly at a desired rate from the system. After the release of drug residual system is emptied from the stomach. This results in increase in gastric residence time and a better control of fluctuation in plasma drug concentration. Development of oral controlled-release systems has been a challenge to formulation scientists because of their inability to restrain and localize the system in the targeted area of the gastrointestinal tract.

O autorze

Dr. Basavaraj K. Nanjwade has completed his Ph.D from Rajiv Gandhi University of Health Sciences Karnataka, Bangalore. He is the Director of KLE Society s College of Pharmacy, Nipani, Karnataka, India. He has published 71 papers in reputed national and international journals and 11 Patents. He guided 19 M.Pharm and 7 Ph. D students