Experimental Glycoscience: Glycochemistry

ISBN-13: 9784431779230 / Angielski / Miękka / 2008 / 252 str.

Naoyuki Taniguchi;Akemi Suzuki;Yukishige Ito

Opis

The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Spis treści

1. Structural Analysis of Sugar Chains Part 1. Release of Sugar Chains and Labeling Part 2. Sequence Analysis Part 3. Sugar Chain Analysis by Mass Spectrometry Part 4. Analysis of the Three-dimensional Structure of Sugar Chains Part 5. Analysis of Sugar?Protein Interactions 2. Chemical Synthesis of Sugar Chains Part 6. Chemical Synthesis of Sugar Chains

O autorze

Naoyuki Taniguchi graduated from the Hokkaido University School of Medicine, followed by an M.D. degree in 1967, and completed the doctoral course of medicine at the Graduate School of Hokkaido University and obtained a Ph.D in 1972. He was then appointed assistant professor at the Hokkaido University School of Medicine in 1975 and was a visiting professor in the group of Dr. Alton Meister at Cornell University Medical College between 1976 and 1977. Returning to Hokkaido University, he joined the Biochemistry Laboratory at the Cancer Institute, before being appointed as a full professor at the Department of Biochemistry, Osaka University Medical School in 1986. Professor Taniguchi is an honorary member of the American Society for Biochemistry and Molecular Biology and has received numerous awards, among them the International Glycoconjugate Organization (IGO) Award in 2001.