Enzyme Handbook

ISBN-13: 9783642489631 / Angielski / Miękka / 2014 / 1177 str.

Dietmar Schomburg; Margit Salzmann

Opis

Enzymes are applied in organic synthesis and in analytical chemistry, in industrial production processes of pharmaceuticals and in food processing. Finding a suitable enzyme for a desired transformation or with a de- fined specificity is not always an easy task. More than 3000 enzymes are well described to date. The Enzyme Handbook provides all the information for selecting the proper enzyme to perform defined transformations in a given environment. The Enzyme Handbook devotes a variable number of pages for each enzyme, depending on the amount of information available with the EC number as ordering criterion within a volume. Revised data sheets can be released for individual enzymes and newly characterized enzymes and they can easily be sorted into the binders at the appropriate place. Each data sheet is divided into 7 sections: - Nomenclature (EC number, Systematic name, Recom- mended name, Synonyms, CAS Reg. No.) - Reaction and specificity (Catalysed reaction, Reaction type, Natural substrates, Substrate spectrum, Product spectrum, Inhibitors, Cofactors/prosthetic groups, Metal compounds/salts, Turnover number, Specific activity, KM-value, pH-optimum, pH-range, Tem- perature optimum, Temperature range) - Enzyme structure (Molecular weight, Subunits, Glyco-/Lipoprotein) - Isolation/Preparation (Source organism, Source tissue, Localisation in source, Purification, Crystallization, Cloned, Renatured) - Stability (pH, Temperature, Oxidation, Organic sol- vent, General stability information, Storage) - Cross-References (to Structure Data Banks) - Literature references

O autorze

The Enzyme Handbook is a concise and complete description of about 3000 enzymes sufficiently well characterized for application in analytical, synthetic and biotechnology processes. The sheets for presently charac- terized enzymes will be published at a frequency of one volume (approx. 200 datasheets) per quarter. After the Enzyme Handbook is complete, revised data sheets and newly characterized enzyme information will be pub- lished at a frequency of approximately 200 data sheets per year (based on the present literature evaluation). Standing orders for the 10 volume series plus up-dates are recommended.