Endothelial Luminal Membrane-Glycocalyx: Functionalities in Health and Disease

ISBN-13: 9781615047543 / Angielski / Miękka / 2017 / 159 str.

Rafael Rubio; Maureen Knabb; D. Neil Granger

Opis

Focuses on the structural, biochemical, and diverse functional properties of the endothelial luminal membrane glycocalyx, an organelle which constitutes the endothelial cell "membrane". This volume provides the newcomer with a broad, basic, and brief perspective of the luminal endothelial vascular membrane, and for the more established investigator, a basic overview and integrated perspective.

Spis treści

• Preface
• Acknowledgments
• PART I THE DISTINCT MORPHOLOGICAL, PHYSICAL, BIOCHEMICAL, AND STRUCTURAL PROPERTIES OF T HE ENDOTHELIAL LUMINAL MEMBRANE-GLYCOCALYX (ELMG)
• 1. The Endothelial Cell in situ is not an Isolated Cell, but a Complex of Cells
• 2. Morphological Structures: Diversity, Heterogeneity, and Appearance Depends on Staining Procedure
• 3. ELMG Structures Responsible for Interacting Forces
• 4. The Diverse Biochemical Composition of the ELMG
• PART II THE DIVERSE STRUCTURAL PROPERTIES OF THE ENDOT HELIAL LUMINAL MEMBRANE-GLYCOCALYX (ELMG) DETERMINE ITS PHYSIOLOGICAL RESPONSES
• 5. Sieving Properties of the ELMG Are Selective and Dynamic and in Series with Active Membrane Transport Systems
• 6. Pharmacological and Compartmentalizing Properties of the ELMG
• 7. Flow Sensing Properties of the ELMG
• PART III PATHOLOGICALLY-INDUCED ALTERATIONS OF ENDOTHELIAL LUMINAL MEMBRANE GLYCOCALYX (ELMG)
• 8. The ELMG in Pathophysiological Conditions
• Author Biographies