Dyes and Drugs: New Uses and Implications

ISBN-13: 9781926692623 / Angielski / Twarda / 2011 / 360 str.

Trimm, Harold H.

Opis

This title includes a number of Open Access chapters. The science of chemistry is so broad that it is normally broken into fields or branches of specialization. The manufacture of drugs and dyes is one of the most practical industrial applications of chemistry. This collection presents the reader with a broad spectrum of chapters on drugs and dyes, thereby demonstrating key developments in this rapidly changing field. It examines dyes in chemical interaction and production of drugs for pharmaceutical use as well as in forensic work and in the production of materials.

Spis treści

Solvent Effect on the Spectral Properties of Neutral Red. The Degradation of Organic Dyes by Corona Discharge. UV-Vis Spectrophotometrical and Analytical Methodology for the Determination of Singlet Oxygen in New Antibacterials Drugs. The Application of Resonance Light Scattering Technique for the Determination of Tinidazole in Drugs. Enhanced Trace-Fiber Color Discrimination by Electrospray Ionization Mass Spectrometry: A Quantitative and Qualitative Tool for the Analysis of Dyes Extracted from Sub-millimeter Nylon Fibers. The pKa Distribution of Drugs: Application to Drug Discovery. Determination of µmol-1 Level of Iron (III) in Natural Waters and Total Iron in Drugs by Flow Injection Spectrophotometry. Design and Synthesis of a Noncentrosymmetric Dipyrromethene Dye. The Function of TiO2 with Respect to Sensitizer Stability in Nanocrystalline Dye Solar Cells. Chromatographic and Spectral Analysis of Two Main Extractable Compounds Present in Aqueous Extracts of Laminated Aluminum Foil Used for Protecting LDPE-Filled Drug Vials. The Cold Contact Method as a Simple Drug Interaction Detection System. NMR and Molecular Modelling Studies on the Interaction of Fluconazole with -Cyclodextrin. Spectrophotometric Determination of Etodolac in Pure Form and Pharmaceutical Formulations. Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034. Pressure-Tuning Raman Spectra of Diiodine Thioamide Compounds: Models for Antithyroid Drug Activity. Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures. Characterization of Thermally Stable Dye-Doped Polyimide Based Electrooptic Materials. Sol-Gel-Derived Silicafilms with Tailored Microstructures for Applications Requiring Organic Dyes. Synthesis and Analysis of Nickel Dithiolene Dyes in a Nematic Liquid Crystal Host. Synthesis of a Photoresponsive Polymer and Its Incorporation into an Organic Superlattice. An Efficient Drug Delivery Vehicle for Botulism Countermeasure. Estimation of Synthetic Accessibility Score of Drug-Like Molecules Based on Molecular Complexity and Fragment Contributions. Rational Mutagenesis to Support Structure-Based Drug Design: MAPKAP Kinase 2 as a Case Study. Nanotechnology Approaches to Crossing the Blood-Brain Barrier and Drug Delivery to the CNS. Index.

O autorze

Dr. Harold H. Trimm was born in 1955 in Brooklyn, New York. Dr. Trimm is the chairman of the Chemistry Department at Broome Community College in Binghamton, New York. In addition, he is an Adjunct Analytical Professor, Binghamton University, State University of New York, Binghamton, New York.

He received his PhD in chemistry, with a minor in biology, from Clarkson University in 1981 for his work on fast reaction kinetics of biologically important molecules. He then went on to Brunel University in England for a postdoctoral research fellowship in biophysics, where he studied the molecules involved with arthritis by electroptics. He recently authored a textbook on forensic science titled Forensics the Easy Way (2005).

William Hunter Jr. graduated from Albany College of Pharmacy and has worked for more than forty years in the pharmaceutical field. He spent the first seventeen of those years in community pharmacy and the latter twenty-five working in a hospital pharmacy. In recent years, in his work at Olean General Hospital, he has had the opportunity to work with some of the most updated pharmaceutical technology, designed to improve both speed and safety in the distribution of medications, leading the hospital into the twenty-first century.