Drugs for Relapse Prevention of Alcoholism

ISBN-13: 9783764302146 / Angielski / Twarda / 2004 / 244 str.

Basskaran Nair; R. Spanagel; Rainer Spanagel

Opis

The field of biomedical research on alcoholism has developed at an unsurpassed speed in recent years. Today new medications and treatment strategies are available and new leads are currently tested in multi-center trials. This book gives a comprehensive overview about different neurotransmitter/peptide systems involved in relapse behavior. The editors - a basic preclinical researcher and a clinical researcher - and some of the most distinguished experts in the field compiled all new available preclinical and clinical data and offer a complete picture on modern relapse prevention. Without a doubt this book provides an entire overview about the topic which will be of interest to the basic researcher, the clinician as well as to the postgraduate and graduate student.

Recenzje

"The book was a delight to read and the editors must be congratulated on bringing together a diverse group of experts to describe both the pre-clinical and clinical aspects of this topical issue. (...) This book will more than fulfil the requirements of a clinician looking for information about the underlying neurobiology of pharmacotherapy."

(Addiction)

Spis treści

History of prevention of relapse.- How to measure relapse in animals.- How to measure relapse in humans.- Disulfiram (Antabuse®): the first medication to stop drinking.- Naltrexone: preclinical data.- Naltrexone: clinical data.- Acamprosate: preclinical data.- Acamprosate: clinical data.- Serotonergic compounds: preclinical data.- Serotonergic compounds: clinical data.- Opioidergic compounds: preclinical data.- Second generation opioidergic compounds: clinical data.- Dopaminergic compounds: preclinical data.- Dopaminergic compounds: clinical data.- Baclofen: preclinical data.- Baclofen: clinical data.- Cannabinoid receptor antagonists: a perspective.- Neuropeptide Y antagonists: a perspective.- Glutamatergic compounds: a perspective.- Future perspectives on relapse prevention.