Drug Synergism and Dose-Effect Data Analysis

ISBN-13: 9781584880455 / Angielski / Twarda / 2000 / 264 str.

Ronald J. Tallarida

Opis

Not since this author's bestselling Manual of Pharmacologic Calculatio n - long out of print - has there been an available reference for drug data analysis. Incorporating the most relevant parts of that work, Dr ug Synergism and Dose-Effect Data Analysis focuses on drug combination s and all the quantitative analysis needed to analyze combination drug data and to design experiments with two or more compounds. Much of th e book is statistical, providing the theory and the computation algori thms needed to analyze single and combination drug data.

Spis treści

Combinations of Chemicals. Dose-Response Analysis. Linear Regression: A Further Discussion. Calculations for Combination Drug Analysis. The Composite Additive Curve. Quantal Dose-Response Data: Probit and Logit Analysis. Analysis of Drug Combinations over a Range of Drug Ratios. Analysis of a Single Dose Combination. Different Experimental Designs. Response Surface Analysis of Drug Combinations. Nonlinear Regression Analysis. Statistical Concepts and Tests of Hypotheses. Appendix.

O autorze

Tallarida, Ronald J.