Diagnosis and Treatment of Parkinson's Disease -- State of the Art

ISBN-13: 9783211832769 / Angielski / Twarda / 1999 / 220 str.

T. Muller; H. Przuntek; Horst Przuntek

Opis

Expert clinicians and basic scientists with a special interest in Park insonFs disease review the current state of science and clinical thera peutics of the disease. Therefore these articles represent an authorat ive review of the current state of knowledge regarding preclinical cou rse and symptomatology, subtypes with their impact on the pathology, g enetic alterations, novel mechanisms of neuronal cell death, diagnosti c tools and old and novel therapeutic approaches with respect to neuro protection and neuroregeneration in ParkinsonFs disease. Particular em phasis has been placed on a novel antiparkinsonian drug called budipin e with various modes of action also influencing altered non dopaminerg ic systems in ParkinsonFs disease. It is evident, that many questions on the cause, course and treatment of ParkinsonFs disease are still un answered and therefore the ideal way to treat a parkinsonian patient r emains to be defined.

Spis treści

Post mortem studies in Parkinson’s disease — is it possible to detect brain areas for specific symptoms?.- Pathogenesis and preclinical course of Parkinson’s disease.- Clinical efficacy of budipine in Pakinson’s disease.- Multiple mechanisms of action: the pharmacological profile of budipine.- Parkinson’s disease: one disease entity or many?.- Parkinson’s disease — a multifactorial neurodegenerative disorder.- Mechanism and consequences of nerve cell death in Parkinson’s disease.- Function imaging of Parkinson’s disease: is it possible to detect brain areas for specific symptoms?.- Multiple system atrophy.- Tremorlytic activity of budipine in Parkinson’s disease.- Current management of motor fluctuations in patients with advanced Parkinson’s disease treated chronically with levodopa.- Differentiation of dopamine agonists and their role in the treatment of Parkinson’s disease.- Free radical scavengers: chemical concepts and clinical relevance.- Differential diagnosis of tremor.

O autorze

Dr. phil. Thomas Müller ist Psychoanalytiker in eigener Praxis in Hanau.