Cleanroom Microbiology for the Non-Microbiologist

ISBN-13: 9780849319969 / Angielski / Twarda / 2004 / 216 str.

David M. Carlberg

Opis

This new edition of Cleanroom Microbiology explains the consequences of microbiological contamination, what contamination is all about, how microorganisms grow, and how they can be controlled. The book also introduces the types, sources, control, and elimination of organisms encountered in the manufacture of sterile products as well as the applications for bacterial detection, avoidance of contamination, and cleanroom design considerations. Several sections of this new edition are revised including eliminating illustrations of obsolete equipment. The author has rewritten the text according to new standards and practices for controlling microbial contamination in cleanrooms.

Spis treści

THE SCOPE OF MICROBIOLOGY
Introduction
Cells
Binomial Nomenclature
Morphology
New! Specific Microbial Groups
New! Taxonomy of Microorganisms
Microscopy
Summary
References

GROWTH OF MICROORGANISMS
Introduction
Growth of Bacteria
New! Growing Other Microorganisms: Fungi, Protozoa, Algae and Viruses
Aseptic Technique
New! Safety Issues
Summary
References

CONTROLLING GROWTH AND ACTIVITIES OF MICROORGANISMS
Introduction
New! Definitions
Physical Methods of Control
New! Assuring Sterility
New! Chemical Methods of Control
Control of Microorganisms in High Purity Water Systems
Summary
References

FACILITIES AND PERSONNEL CONTROLS
Introduction
New! Certified Cleanrooms
New! Bioclean Facilities- Viable vs. Non-Viable Particles
Clean Facilities - General Considerations
New! Unidirectional Air Flow
New! HEPA and ULPA Filters
New! Aseptic Fill Areas
New! Barriers, Clean Zones and Isolators
New! Biosafety Levels
Cleanroom Garments
New! Personnel Practices and Training
New! Personal Hygiene
General Personnel Practices
Summary
References

DETECTION AND ENUMERATION OF MICROORGANISMS IN THE CLEANROOM
Introduction
New! Overview of Microbiological Environmental Monitoring
New! Monitoring of Air
Fallout Methods
Surface Monitoring
New! Touch Plates and Other Personnel Monitoring
Microbiological Assessment of Liquids
Microbiological Assessment of Solids and Semisolids
New! Monitoring for Specific Microorganisms
New! Rapid Methods of Identification
New! Testing for Bacteriostasis and Fungistasis
New! Detection of Biofilms
Sterile Media Fill Tests
Alert and Action Levels
New! The Sterility Suite
Disposal of Cultures
Summary
References

O autorze

David M. Carlberg