Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth-Century Genetics

ISBN-13: 9780415328494 / Angielski / Twarda / 2004 / 236 str.

Hans-Jorg Rheinberger; Jean-Paul Gaudilliere

Opis

With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of mapping procedures as they were developed in classical genetics. An accompanying volume - From Molecular Genetics to Genomics - covers the history of molecular genetics and genomics.

The book shows that the technology of genetic mapping is by no means a recent acquisition of molecular genetics or even genetic engineering. It demonstrates that the development of mapping technologies has accompanied the rise of modern genetics from its very beginnings. In Section One, Mendelian genetics is set in perspective from the viewpoint of the detection and description of linkage phenomena. Section Two addresses the role of mapping for the experimental working practice of classical geneticists, their social interactions and for the laboratory 'life worlds'.

With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contibution to the history of genetics. A companion volume from the same editors - From Molecular Genetics to Genomics: The Mapping Cultures of Twentieth Century Genetics - covers the history of molecular genetics and genomics.

Spis treści

Section 1: Mendelian Genetics and Linkage Mapping 1. Jonathan Harwood . Linkage before Mendelism? Plant-Breeding Research in Central Europe, ca 1880-1910 2. Hans-Jörg Rheinberger. Carl Correns and the Early History of Genetic Linkage 3. Raphael Falk . Applying and Extending the Notion of Genetic Linkage - The First Fifty Years 4. Lisa Gannett and James R. Griesmer. Classical Genetics and the Geography of Genes Section 2: Mapping Work, Mapping Collectives, Mapping Cultures 5. Lee B. Kass and Christophe Bonneuil. Mapping and Seeing: Barbara Mcclintock and the Linking of Genetics and Cytology in Maize Genetics, 1928-35 6. Lisa Gannett and James R. Griesemer . The ABO Blood Groups: Mapping the History and Geography of Genes in Homo sapiens 7. Jean-Paul Gaudillière. Mapping as Technology: Genes, Mutant Mice, and Biomedical Research (1910-65)

O autorze

Hans-Jörg Rheinberger is Director at the Max Planck Institute for the History of Science in Berlin. He has published numerous papers and books in molecular biology and the history of science, including a co-edited collection, The Concept of the Gene in Development and Evolution (2000). Jean-Paul Gaudillière is a senior researcher at the National Institute of Health (INSERM), Paris. His work has addressed many aspects of the history of molecular biology and of the biomedical sciences during the twentieth century. His contemporary research focuses on the history of biological drugs. He is the co-editor of Heredity and Infection: A History of Disease Transmission (2002).