Cellular Lipid Metabolism

ISBN-13: 9783642002991 / Angielski / Twarda / 2009 / 376 str.

Christian Ehnholm

Opis

For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.

Spis treści

1 The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids Sven-Olof Olofsson, Pontus Boström, Jens Lagerstedt, Linda Andersson, Martin Adiels, Jeanna Perman, Mikael Rutberg, Lu Li and Jan Borén 2 Oxysterols and Oxysterol-Binding Proteins in Cellular Lipid Metabolism Vesa M. Olkkonen 3 Cellular Lipid Traffic and Lipid Transporters: Regulation of Efflux and HDL Formation Yves L. Marcel, Mireille Ouimet and Ming-Dong Wang 4 Bile Acids and Their Role in Cholesterol Homeostasis Nora Bijl, Astrid van der Velde and Albert K. Groen 5 Cholesterol Trafficking in the Brain Monique Mulder, Tim Vanmierlo and Dieter Lütjohann 6 Intracellular Cholesterol Transport Daniel Wüstner 7 Role of the Endothelium in Lipoprotein Metabolism Arnold von Eckardstein and Lucia Rohrer 8 Receptor-Mediated Endocytosis and Intracellular Trafficking of Lipoproteins Joerg Heeren and Ulrike Beisiegel 9 Angiopoietin-Like Proteins and Lipid Metabolism Sander Kersten 10 Thyroid Hormones and Lipid Metabolism: Thyromimetics as Anti-Atherosclerotic Agents? Bernhard Föger, Andreas Wehinger, Ivan Tancevski, Josef R. Patsch and Andreas Ritsch 11 Adipokines: Regulators of Lipid Metabolism Oreste Gualillo and Francisca Lago 12 Cellular Cholesterol Transport -- Microdomains, Molecular Acceptors and Mechanisms Christopher J. Fielding 13 The Ins and Outs of Adipose Tissue Thomas Olivecrona and Gunilla Olivecrona