Capillary Electrophoresis in Chiral Analysis

ISBN-13: 9780471974154 / Angielski / Twarda / 1997 / 576 str.

Bezhan Chankvetadze;Chankvetadze

Opis

Capillary electrophoresis (CE) is a separation technique which can separate very small quantities of material. Chiral compounds are molecules which are non-superimposable mirror images of each other.

Spis treści

Partial table of contents:

Basics of Capillary Electrophoresis.

Chiral Metal Complexes as Selectors in Capillary Electrophoresis.

Enantioseparation Using Micellar Electrokinetic Chromatography (MEKC).

Crown Ethers as Chiral Selectors in Capillary Electrophoresis.

Macrocyclic Antibiotics as Chiral Selectors in Capillary Electrophoresis.

Enantioseparation in Capillary Electrochromatography (CEC).

Enantiomer Migration Order in Chiral Capillary Electrophoresis.

Appendix.

Index.

Blurb

Capillary Electrophoresis in Chiral Analysis Bezhan Chankvetadze Tbilisi State University, Republic of Georgia The application of capillary electrophoresis (CE) to the field of chiral analysis has exploded recently. The advantages of capillary electrophoresis – extremely high peak efficiency, excellent compatibility with biological samples, short analysis time, simplicity, versatility and low cost – are perfect for the accurate measurement of optical purity, increasingly important in the regulation–ruled pharmaceutical industry. Although there have been a number of books on capillary electrophoresis and chiral analysis separately, as yet there has been no dedicated monograph on the application of capillary electrophoresis to chiral analysis. This book bridges the gap. Capillary Electrophoresis in Chiral Analysis charts the evolution of chiral capillary electrophoresis and describes new types of chiral selectors and mechanistic aspects of chiral recognition. While on the one hand, it is an excellent introduction to newcomers, on the other, it is of practical use to experienced researchers in the field wishing to solve a particular separation problem. It includes an alphabetical list of chiral compounds resolved using CE with appropriate references, which any one working in the field will find invaluable.