CNS Injuries: Cellular Responses and Pharmacological Strategies

ISBN-13: 9780849383090 / Angielski / Twarda / 1998 / 240 str.

Martin Berry; M. Berry; Ann Logan

Opis

The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an up-to-date examination of new developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including

inflammatory and immune reactions

scarring

neuron death

demyelination and remyelination

axonal regeneration

re-establishment of neuronal connectivity
Providing a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others.

Spis treści

Cellular Responses to Penetrating CNS Injury, M. Berry, A. Butt, and A. Logan
Cellular Responses to Ischaemic CNS Injury, W.L. Maxwell
The Immune Response and CNS Injury, N.A. Gregson
Haematogenous Cell Responses to CNS Injury, K.A. Brown and B.A. Khoshkbijari
Role of Macrophages and Microglia in the Injured CNS, W.J. Streit
Cellular Trafficking, A.J. Vora and K.A. Brown
Protease Inhibitors and Microglia/Macrophage-Modulating Drugs Prevent Microglia-Mediated Neuronal Death in the Traumatised and Dystrophic Retina, S. Thanos, R. Naskar, and P. Heiduschka
Transforming Growth Factor-b and CNS Scarring, A. Logan and M. Berry
Neurotrophic Factors, T. Hagg
Fibroblast Growth Factors, C. Grothe, C. Meisinger, and K. Wewetzer
Index

Audience

O autorze

Martin Berry