Bioresponse-Linked Instrumental Analysis

ISBN-13: 9783519003168 / Angielski / Miękka / 2001 / 195 str.

Bertold Hock

Opis

Die wirkungsbezogene Analytik befasst sich mit der engen Kopplung von Biotests mit der chemischen Analytik. Hierbei werden die biomolekulare Erkennung, die im Organismus einen biologischen Effekt auslost, und die chemische Analytik kombiniert. Dieses Buch behandelt Fortschritte in der analytischen Instrumentation von biologischen Makromolekulen, welche die gekoppelten Technologien ermoglicht haben, insbesondere die automatische Kopplung von Bindungstests mit der chemischen Analytik.

Spis treści

Approaches to Bioresponse-Linked Instrumental Analysis - Detection of Bioeffective Environmental Componds by High-Performance Thin Layer Chromatography - Electronic Noses - Receptors as Analytical Tools for Bioresponse - Bioresponse-Linked Analysis Based on Acetylcholinesterase Inhibition - Transport Proteins in Blood - Biomonitor Systems Derived from Thylakoids for the Detection of Phytotoxic Substances

O autorze

Professor Dr. Bertold Hock, Technische Universität München

Blurb

Bioresponse-linked instrumental analysis combines biomolecular recognition, initiating a biological effect in the organism, and chemical analysis. Although this technology is only at its beginning, the power of this approach is obvious. It provides both, information on effects with respect to the applied target structures as well as the chemical structure and concentration of active substances present in a sample. In this book, examples ranging from endocrine disruptors to neurotoxic substances are used to illustrate the principle.