Biopolymeric Magnetic Nanocarriers for Controlled drug release : Evaluation of drug release behaviour by polymeric nanocomposites

ISBN-13: 9783659933547 / Angielski / Miękka / 2018 / 88 str.

Anamika Singh; Anil Kumar Bajpai; Jaya Bajpai

Opis

Bipolymeric magnetic nanoparticles for controlled release involve the synthesis of polymeric nanoparticles and evaluation of their drug release potential used for Magnetic drug targeting. Magnetic drug targeting is a drug delivery system that can be used in cancer treatment. Coated magnetic particles, called carriers, are very useful for delivering chemotherapeutic drugs. In the present research casein coated iron oxide nanocarriers (CCIONPs) of core shell nanostructure have been described to find application in magnetic drug targeting. The nanoparticles were loaded with cytarabine drug and its controlled release was investigated as a function of drug loading, chemical architecture of the nanocarriers, and nature of release media. Drug release data were examined by some kinetic models like zero-order, first order, and Higuchi.

O autorze

Singh, Anamika
Ms. Anamika Singh is currently working in CSIR-CDRI as a post doctoral researcher. She did her post graduation in chemistry in 2010 and joined Ph.D. under the supervision of Prof. Anil Kumar Bajpai. She has expertise on designing of natural based nanocarriers for delivery of anticancer and antitumor drugs for treatment of complex diseases.