Biological Magnetic Resonance: In Vivo Carbon-13 NMR

ISBN-13: 9781475789027 / Angielski / Miękka / 2013 / 255 str.

Lawrence J. Berliner; Pierre-Marie Robitaille

Opis

This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of the stable isotope 13-C. The 13-C is used to probe the chemistry, mechanism, and function in living systems.
All the chapters are written by experts in the field who discuss topics such as Tracer Theory and the Suitability of 13-C NMR', Applications of 13-C to Studies of Human Brain Metabolism', etc.

Recenzje

`An excellent collection of review articles ... A significant compilation of the theoretical basis of emerging technologies and a summary of their successes.'
Journal of the American Chemical Society
`The reviews presented are diverse in nature ... continue to provide fresh analysis of the latest science ... succeed in being comprehensive in the subject areas.'
Trends in Analytical Chemistry

Spis treści

Tracer Theory and 13C NMR; M.R. Laughlin, J.K. Kelleher. 13C Isotopomer Analysis of Glutamate: An NMR Method to Probe Metabolic Pathways Intersecting in the Citric Acid Cycle; A.D. Sherry, C.R. Mally. Determination of Metabolic Fluxes by Mathematical Analysis of 13C Labeling Kinetics; J.C. Chatham, E.M. Chance. Metabolic Flux and Subcellular Transport of Metabolites; E.D. Lewandowski. Assessing Cardiac Metabolic Rates during Pathologic Conditions with Dynamic 13C NMR Spectra; R.G. Weiss. Applications of 13C Labeling to Studies of Human Brain Metabolism in Vivo; G.F. Mason. In Vivo 13C NMR Spectroscopy: A Unique Approach in the Dynamic Analysis of Tricarboxylic Acid Cycle Flux and Substrate Selection; P.-M. Robitaille. Index.

O autorze

Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.