Biological Inorganic Chemistry : A New Introduction to Molecular Structure and Function

ISBN-13: 9780128117415 / Angielski / Miękka / 2018 / 692 str.

Universite Catholiq Robert R. (Unite de Biochimie Crichton

Spis treści

Part 1 Basic Principles 1. An overview of the role of metals in biology 2. Basic coordination chemistry for biologists 3. Structural and molecular biology for chemists 4. Biological ligands for metal ions 5. An overview of intermediary metabolism and bioenergetics 6. Methods which can be used to study metals in biology 7. Metal assimilation pathways 8. Transport, storage and homeostasis of metal ions

Part 2 Metals in Biology 9. Sodium and potassium - Channels and Pumps 10. Magnesium - phosphate metabolism and photoreception 11. Calcium - cellular signalling 12. Zinc - Lewis acid and gene regulator 13. Iron - essential for almost all life 14. Copper - Coping with Dioxygen 15. Nickel and Cobalt - evolutionary relics 16. Manganese -oxygen generation and detoxification 17. Molybdenum, Tungsten, Vanadium and Chromium 18. Non-metals in biology 19. Biomineralisation

Part 3 Metals in Medicine and the Environment 20. Metals in brain function 21. Metal-based Neurodegeneration 22. Metals in medicine and metals as drugs 23. Metals in the environment

O autorze

Robert Crichton is Emeritus Professor, Faculty of Science, Universite Catholique de Louvain in Belgium. He has some forty years experience in teaching the subject, and published over 200 scientific articles and a number of books. Since 1985 he has organized a series of over twenty advanced courses on Metals in Biology in Louvain-la-Neuve, which have trained over 1300 doctoral and post-doctoral students, many of whom are today leaders in the field.

The Second Edition of Biological Inorganic Chemistry: An Introduction to Molecular Structure and Function received the 2013 TEXTY Textbook Excellence Award in Physical Sciences from the Text and Academic Authors Association.