Biological Approaches to Rational Drug Design

ISBN-13: 9780849394225 / Angielski / Twarda / 1994 / 224 str.

David B. Weiner;William V. Williams

Opis

Intended for medicinal chemists, pharmaceutical scientists, pharmacologists, immunologists, biochemists and microbiologists, this book provides both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It offers state-of-the-art approaches to pharmaceutical development, including biological technologies currently used by some of the world's foremost laboratories. Features include: discussion of new techniques; previously unpublished data; and extensive reference lists.

Spis treści

Identifying Lead Peptides from Epitope Libraries, J.K. Scott
Interleukin-1 Receptor Pathway Approaches to Drug Design, H.M. Einspahr, B.C. Finzel, and D.E. Tracey
The Hematopoietic Colony-Stimulating Factors, K. Kaushansky
Monoclonal Antibodies: Technical Development and Therapeutic Indications, M.R. Dalesandro, M.E. Sanders, and J.A. Lipani
T Cell Receptor-Based Therapy of Autoimmune Diseases, T. Ramanujam and W.V. Williams
Oligosaccharide Pharmaceuticals, S. Roth and D. Zopf
Gene Therapy, J.D. Boyer and D.B. Weiner
Antisense Deoxynucleotides and Ribozymes: Mechanisms of Action and Potential in Gene Therapy, S.K. Shore and E.P. Reddy
Index

O autorze

David B. Weiner (University of Pennsylvania, Philadelphia, USA) (Edited by) , William V. Williams (University of Pennsylvania School of Medicine, Philadelphia,) (Edited by)