Bioactive Conformation I

ISBN-13: 9783540490777 / Angielski / Twarda / 2007 / 309 str.

Opis

This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts - it is still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. The book will appeal to scientists and practitioners in the mentioned fields and in industry.

Recenzje

From the reviews:

"Bioactive Conformation I contains eight chapters on quite different topics within the theme of the series. ... it will be essential reading for any researcher working in any area that involves binding of a substance to a protein." (T. B. Grindley, Journal of the American Chemical Society, Vol. 130 (2), 2008)

Spis treści

T. Weide, A. Modlinger, H. Kessler: Spatial Screening for the Identification of the Bioactive Conformation of Integrin Ligands.- S. W. Homans: Dynamics and Thermodynamics of Ligand-Protein Interactions.- N.J. Harmer: The Fibroblast Growth Factor (FGF) – FGF Receptor Complex: Progress Towards the Physiological State.- B. Reif, S. Narayanan: Characterization of Interactions Between Misfolding Proteins and Molecular Chaperones by NMR Spectroscopy.- D. Fischer and A. Geyer: NMR Analysis of Bioprotective Sugars: Sucrose and Oligomeric (1® 2)-a-D-Glucopyranosyl-(1® 2)-ß-D-Fructofuranosides.- B.W. Koenig: Residual Dipolar Couplings Report on the Active Conformation of Rhodopsin-Bound Protein Fragments.- B. Schuman, J.A. Alfaro, S.V. Evans: Glycosyltransferase Structure and Function.- S.R. LaPlante: Exploiting Ligand and Receptor Adaptability in Rational Drug Design Using Dynamics and Structure-Based Strategies