Asymmetric Cell Division in Development, Differentiation and Cancer

ISBN-13: 9783319531496 / Angielski / Twarda / 2017 / 421 str.

Jean-Pierre Tassan; Jacek Z. Kubiak

Opis

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.

Spis treści

1. Ismael Sánchez-Osorio, Carlos A. Hernández-Martínez , Agustino Martínez-Antonio, Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach  ama@biosintetica.mx 

 

2. John J. Tyson, Kartik Subramanian, Spatiotemporal models of asymmetric cell division cycle in Caulobacter crescentus    skartik@vt.edu  

 

3. Marco Geymonat, Marisa Segal, Intrinsic and extrinsic determinants linking spindle pole fate, spindle polarity and asymmetric cell division in the budding yeast S. cerevisiae  ms433@cam.ac.uk  

 

4. Arielle Koonyee Lam, Bryan Phillips, Wnt signaling polarizes C. elegans asymmetric cell divisions during development  bryan-phillips@uiowa.edu

 

5. Anne Pacquelet, Asymmetric cell division in the one-cell C.elegans embryo: multiple steps to generate cell size asymmetry      anne.pacquelet@univ-rennes1.fr       

 

6. Jerome Teuliere, Gian Garriga, Size matters: how C. elegans asymmetric divisions regulate apoptosis garriga@berkeley.edu  

 

7. Christian Pohl, The midbody and its remnant in cell polarization and asymmetric cell division   Pohl@em.uni-frankfurt.de

 

8. Emmanuel Gallaud, Tri Than Pham, Clemens Cabernard , Drosophila melanogaster neuroblasts: a model for asymmetric stem cell divisions   clemens.cabernard@unibas.ch    

 

9. Malgorzata Kloc, Jacek Z. Kubiak, Szczepan Bilinski, Asymmetric divisions in oogenesis MKloc@houstonmethodist.org      

 

10. Radek Sindelka, Monika Flachsova, Pavel Abaffy and Mikael Kubista, Asymmetric localization and distribution of factors determining cell fate during early development of Xenopus laevis  mikael.kubista@ibt.cas.cz                 

 

11. Guillaume Hatte, Jacek Z. Kubiak, Jean-Pierre Tassan, Asymmetries in cell division, cell size and furrowing in the Xenopus laevis embryo jean-pierre.tassan@univ-rennes1.fr   

 

12. Takefumi Negishi, Hiroki Nishida, Asymmetric and unequal cell divisions in ascidian embryos  hnishida@bio.sci.osaka-u.ac.jp

 

13. Agathe Chaigne et Marie-Emilie Terret, Marie-Hélène Verlhac, Asymmetries and symmetries in the mouse oocyte and zygote   marie-helene.verlhac@college-de-france.fr  

 

14. Damian Dudka, Patrick Meraldi, Symmetry does not come for free – cellular mechanisms to achieve a symmetric cell division  Patrick.Meraldi@unige.ch  

15. Clare L. Garcin, Shukry J. Habib, A Comparative Perspective on Wnt/β-catenin Signalling in Cell Fate Determination   shukry.habib@kcl.ac.uk       

 

16. Prestina Smith, Mark Azzam, Lindsay Hinck, Extracellular regulation of the mitotic spindle and fate determinants driving asymmetric cell division  lhinck@ucsc.edu 

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17. Ian Meyers, Mathieu Daynac, Claudia Petritsch, Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells    Claudia.Petritsch@ucsf.edu

 

18. Subhas Mukherjee, Daniel J. Brat, Molecular programs underlying asymmetric stem cell division and their disruption in malignancy       dbrat@emory.edu       @emory.edu