Aptamers: Biotechnological Applications of a Next Generation Tool

ISBN-13: 9789811388385 / Angielski / Miękka / 2020 / 186 str.

Gulab Singh Yadav; Vikas Kumar; Neeraj K. Aggarwal

Spis treści

1. Aptamer – The science of synthetic DNA

2. Recent updates for isolation of aptamers for various biothreat agents using different strategies and their role in detection applications

3. Aptamer: Apt Targeted Delivery System

4. Aptamers: Novel therapeutic and diagnostic molecules.

5. Aptamers: A Futuristic Approach in diagnosis via antibody substitution.

6. Aptamer conjugated drugs

7. Aptamer based protein activity regulation

8. Aptasensor; Possible design and strategy for aptamer based sensor.

9. Aptamer based biosensors for detection of environmental pollutants

10. Aptamer based target identification in Plants

11. Role of aptamer in Plant defense mechanism

12. Aptamer- a next generation tool for application in agricultural industry for food safety

 

O autorze

Dr. Gulab Singh, presently working as Young scientist in Central University of Haryana, on the topic related to removal of toxicants such as aflatoxin and ochratoxin from environment with help of Nanotechnology. He has published more than 25 research publication and reviews in journals of national and international repute and also one of the Editor of book “Microbiology and Biotechnology for sustainable environment” published by Nova science publication, USA. His area of interest in research is Bio-nanotechnology and its application in detection and management of environmental pollution and food contaminants. He has filed Six Indian patent on detection of contaminant in food and water.

 

Dr. Vikas Kumar, currently serving as Assistant Professor in Maharishi Markandeshwar University, Mullana (Ambala) and has guided several M.Sc., M. Tech and one Ph,D student during their research work.  He has published more than thirty research papers and reviews in journals of national and international repute and contributes regularly to society. He has been also acting as the associate editor and reviewer of various journals. As a researcher, his research interest includes areas like biological control agents, antimicrobial activity of compounds and plant pathology field. Editor of One Book published by Nova science publication, USA

 

Dr. Neeraj K. Aggarwal is presently working as a Chairman in the Department of Microbiology, Kurukshetra University, Kurukshetra, India. He is having more than 12 years of research and teaching experience of post-graduation classes. He has guided 15 Ph. D research students and presently Six students are working under his guidance. He is gold medalist and has been awarded prestigious S R Vyas gold medal for being best microbiological research worker. He has published more than 120 research papers, reviews and book chapters in various journals of national and international repute. He also authored a popular text book Introduction to Biotechnology for B. Tech. students and also one of the editor of Book published by Nova science publication, USA. He is a member of various academic and professional bodies. His research area includes microbial biotechnology for different metabolites, biomass valorization, molecular genetics and biological control agents.

Blurb

The book discusses the basics of aptamers and the advent of aptamer-based technology in recent times. The book covers the diverse applications of aptamers, such as in detection of animal and plant pathogens, disease diagnosis and therapeutics, environmental contamination detection etc. Besides these applications, the book also describes the use of these synthetic or modified DNA, as drug delivery vehicles.

The different chapters describe how the binding capacity and specificity of aptamers can be exploited in various ways. The book also discusses how these attributes of aptamers can outdo the antibody technology in biomedical and diagnostic solutions. This crisp and concise book gives the readers an insight into the most recent biotechnological applications of aptamers.