Anthropic Awareness: The Human Aspects of Scientific Thinking in NMR Spectroscopy and Mass Spectrometry

ISBN-13: 9780124199637 / Angielski / Twarda / 2015 / 464 str.

Szantay, Jr., Csaba

Opis

Anthropic Awareness: The Human Aspects of Scientific Thinking in NMR Spectroscopy and Mass Spectrometry blends psychology, philosophy, physics, mathematics, and chemistry, describing a human-centered philosophy of the essence of scientific thinking in the natural sciences and in everyday life. It addresses the reasons why we are prone to make errors in our conclusions and how to avoid such mistakes, also exploring a number of the "mental traps" that can lead to both individual mistakes and mass misconceptions. The book advocates that by understanding the nature of these mental traps we can adopt tactics to safely evade them. It includes Illustrative examples of common scientific misunderstandings and mental traps in both the theory and real-life application of NMR spectroscopy and mass spectrometry.

• Provides strategies on how to deal with molecular challenges and instrument limitations
• Presents multiple applications of small molecule structure elucidation using NMR, MS, IR, and UV
• Explores critical topics, including anthropic awareness (AA), NMR Spectroscopy, mass spectrometry, scientific thinking, and more
• Includes tactics on how to Improve quality control and data interpretation skills while minimizing data analysis time and increasing confidence in results
• Presents coverage on tactics to optimize experimental NMR parameters and enhance NMR vocabulary

Recenzje

"Reading this book made me even more aware of how much caution one needs to exercise to avoid confirming what one wants to believe.an excellent lesson for everyone in science, although admittedly people working in synthesis and/or structure elucidation will be the ones appreciating it the most." --Analytical and Bioanalytical Chemistry

Spis treści

PrefacePart I. Anthropic Awareness (AA)1. The philosophy of 'Anthropic Awareness' in scientific thinkingPart II. AA in why-science: examples from NMR theory2. An 'anthropically' flavored look at some basic aspects of NMR spin physics using a classical description3. The ups and downs of NMR described by classical and quantum mechanics4. The RF pulse and the Uncertainty Principle5. On the nature of the RF driving field in NMR (with a look out on optical rotation)Part III. AA in what-science: small-molecule structure elucidation by NMR and MS6. An 'anthropic' modus operandi of structure elucidation by NMR and MS7. NMR methodological overview8. MS methodological overview9. Computer assisted structure elucidation in NMR10. Structure elucidation of a mysterious trace component of ulipristal actetate11. The adventurous discovery of the structure of a novel vincristine impurity12. An elusive degradation product of ziprasidone13. The case of an emotion- and 'emotycs'-laden structure determination of a small synthetic molecule with an unexpected structure14. Self-induced recognition of enantiomers (SIRE) in NMR spectroscopy15. Believe it or not: carbon protonation of the pyrimidine ring