Animal Models of Neurological Disease, I: Neurodegenerative Diseases

ISBN-13: 9781489940223 / Angielski / Miękka / 2013 / 368 str.

Alan A. Boulton; Glen B. Baker; Roger F. Butterworth

Opis

The use of animal models continues to be the most reliable way of studying pathophysiologic mechanisms as well as treatments for neurological disorders. In two companion volumes, Animal Models of Neurological Disease highlights new information and techniques available in this rapidly growing area.
This volume of Neuromethods focuses on commonly studied neurodegenerative diseases, highlighting the similarities and differences between the human condition and that obtained using animal models. Chapters are contributed by experts in the field and cover a variety of topics, including: the ethics of using animal models Alzheimer's disease Huntington's disease Parkinson's disease Lesch-Nyhan disease genetic and nongenetic demyelinating diseases cerebellar ataxias rodent and primate models surgical lesions neurotoxins.
Boulton, Baker, and Butterworth's important new treatise on Animal Models of Neurological Disease is an outstanding guide for all researchers striving for a better understanding of neurological disease."

Recenzje

These books go out of their way to be helpful. Most chapters introduce the animal models against the background of the human (i.e., clinical) context and conclude with a brief summary. Detailed experimental protocols and useful tabulations abound. Descriptions are exhaustive.-Trends in Neurosciences

Spis treści

Ethics of Animal Models of Neurological Diseases. Animal Models of Alzheimer's Disease. Animal Models of Huntington's Disease. Rodent Models of Parkinson's Disease. Primate Models of Parkinson's Disease. Genetic Dysmyelination Models: A Key to the Mechanisms and Regulation of Myelination. Nongenetic Animal Models of Myelin Disorders. Animal Models of the Cerebellar Ataxias. Animal Models for Lesch-Nyhan Disease. Index.