Anatomy of Gene Regulation: A Three-Dimensional Structural Analysis

ISBN-13: 9780521800303 / Angielski / Twarda / 2003 / 298 str.

Panagiotis A. Tsonis

Opis

Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. This concise and unique synthesis and its accompanying web site offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states.

Recenzje

'So this book presents a very wide-ranging coverage of three-dimensional structural aspects only in a concise and attractive format with very readable text … I enjoyed this book as a handy source to dip into for structural insights and for the author's obvious pleasure in communicating these to his audience.' Heredity

Spis treści

Preface; 1. A general introduction to 3-D structures; 2. The higher organization of the genome; 3. Structure of DNA and telomeres; 4. DNA replication; 5. Transcription in prokaryotes; 6. Transcription in eukaryotes; 7. Splicing; 8. Modifications of mRNA; 9. Compartmentalization of transcription; 10. Protein synthesis; 11. The birth and death of proteins; Index.