Analysis of Quantal Response Data

ISBN-13: 9780412317507 / Angielski / Twarda / 1992 / 532 str.

Byron J. T. Morgan; B. J. T. Morgan; Morgan J. T. Morgan

Opis

Quantal response (sometimes called dose-reponse) data arise in many areas, both through experimental and observational studies. Particular emphasis is placed in this book on applications in bioassay and toxicology. For instance, data for analysis may arise from routine clinical trials, or from studies of safe doses of drugs. Throughout the material is motivated by a wide range of practical examples.

Recenzje

"This book is a welcome addition to the analysis of dose-response quantal bioassays which are so important in toxicology and pharmacology...it contdains the best collection and description of all known methods in bioassays."
-Short Book Reviews of the ISI

"...a thorough and readable reference..."
-Technometrics

"I believe that this book should be in the library of all applied statisticians...an excellent reference. It serves as a model for books on statistical methods in special areas and is a worthy successor to Finney's work, which has dominated the field for so long."
-Journal of the American Statistical Association

Spis treści

1. Data, preliminary analyses and mechanistic models 2. Maximum-likelihood fitting of simple models 3. Extensions and alternatives 4. Extended models for quantal assay data 5. Describing time to response 6. Over-dispersion 7. Non-parametric and robust methods 8. Design and sequential methods

O autorze

Morgan\, Byron J.T.