Allosteric Modulation for Drug Discovery

ISBN-13: 9781118568576 / Angielski / Twarda / 2020 / 608 str.

Huailing Zhong;Lauren T. May

Opis

A bridge for industrial and academic collaborations, this book overviews the concepts and therapeutic application of allosteric modulation to control protein function - explaining why it has gained strong momentum in drug discovery, technologies and methodologies to discover allosteric modulators, and allosteric modulator compounds.

- Collects into one single resource the details on allosteric modulation of key drug targets, making for an encyclopedic coverage from basics to drug discovery applications
- Describes methods to detect and analyze allosterism
- Lets readers compare how allosteric modulators function and used across different platforms
- Includes the major drug target classes with demonstrated allosteric modulation
- Features a companion website with color images and protocols that readers can access