Advances in Molecular Toxicology: Volume 3

ISBN-13: 9780444533579 / Angielski / Twarda / 2009 / 233 str.

Fishbein, James C.

Opis

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.
Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed.

* Cutting-edge reviews by leading workers in the discipline
* In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines
* Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine

Spis treści

1. Recent developments in Mediterranean harmful algal events
2. Mechanism of fiber carcinogenesis: From extranuclear target to Transforming Growth Factor signaling pathway
3. Applications of quadrupole-linear ion trap mass spectrometry to the analysis of reactive metabolites in drug discovery and development
4. Molecular aspects of neurotoxins in dopaminergic neurons
5. Molecular mechanisms of 4 (methylnitrosamino)-1-(3 pyridyl)-1 butanone-induced lung carcinogenesis
6. Disruption of heme synthesis by polyhalogenated aromatics
7. Triplet carbonyls: A neglected family of reactive oxygen species