Advances in Molecular Toxicology: Volume 2

ISBN-13: 9780444530981 / Angielski / Twarda / 2008 / 246 str.

James C. Fishbein

Opis

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.
Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed

* Cutting edge reviews by leading workers in the discipline.
* In depth dissection of molecular aspects of interest to a broad range of scientists, physisicans and any student in the allied disciplines.
* Leading edge applications of technological innovations in the chemistry, biochemistry and molecular medicine.

Spis treści

1. Genotoxicity of Chromate
James J. Covino and Kent D. Sugden

2. Drug-Induced Hepatotoxicity:
Learning from Recent Cases of Drug Attrition
Axel Pähler and Christoph Funk

3. Glucuronidation-Dependent Toxicity and Bioactivation
Benedetta C. Sallustio

4. Allergic Contact Dermatitis - A Common Skin Disease Caused by Allergic Reactions to Chemicals in Our Environment
Ann-Therese Karlberg, Jens Baron and Hans Merk

5. Inorganic Molecular Toxicology and Chelation Therapy of Heavy Metals and Metalloids
Graham N. George, Ingrid J. Pickering, Christian J. Doonan, MalGorZata Korbas, Satya P. Singh and Ruth E. Hoffmeyer

6. Pyrimidine Damage and Repair
Agus Darwanto, Lynda Ngo and Lawrence C. Sowers

7. Formation, Persistence and Significance of DNA Adduct Formation in Relation of Some Pollutants from a Broad Perspective.
Annie Pfohl-Leszkowicz