Advances in Forensic Haemogenetics: 12th Congress of the Society for Forensic Haemogenetics (Gesellschaft Für Forensische Blutgruppenkunde E.V.) Vienn

ISBN-13: 9783540187653 / Angielski / Miękka / 1988 / 657 str.

Wolfgang R. Mayr

Opis

Publication of papers presented at the 12th International Meeting for Forensic Haemogentics Wien 1987. Topics covered included: Formal genetics, population genetics, biochemistry and serology of nearly all hereditary blood group poly- morphisms. Also several reviews of e.g. enzyme polymor- phisms; problems and aspects of the application for paternity testing; extensive articles on forensic stain information with numerous new methods and description of artifacts; polymorphisms in body fluids; quality control methods; use of biostatistics in forensic haemogentics.

Spis treści

I. Alloantigens.- Alloantigens on Red Blood Cells.- Biochemistry of Red Blood Cell Antigens: Carbohydrate Antigens.- Alloantigens of Proteins and Glycoproteins in Membranes of Human Red Blood Cells.- Studies on the Landsteiner’s Model.- Biochemical Characterization of Class VII and VIII Cells within the Miltenberger System.- Flow Cytometry: An Alternative Quantitative Method to Determine Antigen Zygosity and Its Application to Paternity Testing.- Application of Lectins in Forensic Serology: A Simple Practical Method to Establish Source of Blood.- Testierungsresultate einiger seltener Blutgruppen.- ABO Incompatibility, Immunocytochemical Findings in Hemolytic Transfusion Reactions.- Alloantigens on White Blood Cells.- Alloantigens on Leukocytes and Platelets: Biochemistry (Abstract).- HLA Polymorphisms in Southern African Populations.- Erfahrungen mit der HLA-DR-Typisierung in der Vaterschaftsserologie.- Serology as a Tool for Identification of Dead Bodies.- Personal Identification by HLA Typing of Cultured Fibroblast Derived from Cadaveric Tissues.- Alloantigens on Plasma Proteins.- Polymorphisms of Immunoglobulins: Gm, Am and Km Typing.- Investigations into the Inheritance of Serum IgD Concentration.- II. Electrophoretic Polymorphisms.- Red Cell Enzymes.- Isoenzyme.- Human Red Cell Acid Phosphatase (ACP1): Evidence for Differences in the Primary Structure of the Two Isozymes Expressed by Each Allele.- ACP1 Polymorphism: Five New Variants Detected by Multiple Electrophoretic Methods.- Discrepancy Between Gene and Protein Products Within the PGM1, System Shown by Improved Resolution on Immobiline Gels.- On the Significance of Isolated Exclusions in the PGM1 Subtype System.- Phenotyping Adenosine Deaminase Using Ultra-Thin Isoelectric Focusing.- PGD Duisburg: A New Variant of 6-Phosphogluconate Dehydrogenase.- A New Variant of Galactose-1-Phosphate-Uridyltransferase (Gt Oron).- Frequencies of the Red Cell Uridine-5-Monophosphate Kinase Groups (UMPK), E.C.2.7.4.14, in Schleswig Holstein.- Incidence of Rare Variants Among Serum Proteins and RBC Enzymes in US Whites and Blacks.- Proteins in Plasma and Urine.- Genetic Polymorphisms of Complement Components and Other Plasma Proteins.- C3-Subtypes Demonstrated by “Home-Made Immobiline” Generated Immobilized pH Gradients and Immunoblotting, Frequency Analysis for Hannover and Lower Saxony, FRG (Abstract).- Verbesserte C4-Typisierung durch IAGE Neuraminidase- und Carboxy-Peptidase B-behandelter EDTA-Plasmen.- Die Darstellung der humanen C6-Allotypen durch IAGIEF.- Subtyping of Factor B by Agarose Gel Electrophoresis.- Haptoglobin (Hp) Subtypes in the German Rhine-Ruhr Area.- Patterns and Frequencies of Common and Rare Hp ?-Chain Variants.- Subtyping of Hp: Common and Rare Phenotypes.- The Distribution of Hp Subtypes in Sweden.- Studies into Structure and Inheritance of the Genetical Hp Ca-Variant.- Classification of Alphal Antitrypsin Phenotypes by HighResolution Two-Dimensional Electrophoresis (2-D PAGE).- Characterization of Transferrin Subtypes by Hybrid IEF on Ultrathin Polyacrylamide Layers.- Tf, Pi and Gc Variants: A Study by Isoelectric Focusing with Immobilized pH Gradients.- Agarose Isoelectric Focusing for Classification of Plasminogen-Variants.- Improved FXIIIB-Phenotyping by Isoelectric Focusing with Immobilized pH-Gradients.- Orosomucoid (ORM) Subtyping: Application to Paternity Testing.- Improved Diagnosis of Orosomucoid (ORM) Phenotypes by Isoelectric Focusing in Immobilized pH Gradients. Comparison With Other Phenotyping Methods.- Genetic Study of Serum Orosomucoid (ORM) Polymorphism by Ultrathin Layer Isoelectric Focusing.- Polymorphism of Orosomucoid (ORM), Formal Genetics and Population Data.- ?2-HS-Glycoprotein: Improved Phenotyping by Focusing in an Immobilized pH-Gradient. Allele Frequencies in a South German Population Sample and Linkage Data from a Large Pedigree.- Polymorphism of AHS-Glycoprotein: Comparison of Different IEF and Detection Techniques.- Genetic Polymorphism of Urinary Pepsinogen (PGA) Detected by Immunoblotting.- Electrophoretic Transfer of Proteins from Electrofocusing Gels Cast on a Plastic Support Film.- Eine Methode zur schnellen und kostengünstigen Analyse geringer Probenmengen mittels IEF in dünnen Gelen (Abstract).- Silent Alleles.- Contrary Homozygosity of the PGM1, System in Disputed Paternity.- Nachweis des „stummen Gen“ PGP° am Phosphoglycolat-Phosphatase-Locus.- “Silent” Alleles in Paternity Testing.- Further Evidence of a Silent TF Allele.- Incidence of the PLG*QO Allele in Human Populations.- III. Monoclonal Antibodies.- Some Recent Aspects on Hybridoma Technology.- The Application of Monoclonal Antibodies for the Definition of Genetic Markers on Human Red Cells.- The Use of Monoclonal Antibodies in Forensic Science.- Specificity of the Monoclonal Antibody and its Application to Forensic Medicine.- Monoclonal Anti-D: Reactivity with Various D Phenotypes.- Monoclonal Antibodies Specific for Ag c/g and Ag a1/d Polymorphism of Human Low Density Lipoprotein.- The Use of Monoclonal Antibodies for the Detection of Red Cell Antigens in Stain Material.- IV. DNA Polymorphisms.- Recombinant DNA Technology and Human DNA-Polymorphism.- DNA Polymorphisms - Practical Use.- A Protokoll Using an Alkali Blotting Procedure for the Analysis of Restriction Length Fragments of Human DNA.- Identifying DNA RFLP’s in Routine Paternity Cases: Non-Isotopic Methods of Detection.- The Application of DNA-Print for the Estimation of Paternity.- Ein Vergleich von 25 Blutgruppensystemen mit polymorphen DNA-Markern in der Vaterschaftsbegutachtung.- Comparison of Cost Benefit Between Traditional Paternity Systems and RFLP Analysis (Abstract).- RFLP als zusätzliches System in der Abstammungsbegutachtung.- An Evaluation of the Use of DNA Probe hMF1 in Cases of Disputed Paternity by Comparison with a Range of Well Established Blood Group Polymorphisms.- Allelic Frequency of Polymorphic DNA Sequences in Japanese and its Application to the Paternity Testing.- Restriction Site Polymorphism (RFLP) Detected with pG3PD and Taq 1.- Segregation Analysis and Determination of Parentship by Use of RFLP’s Corresponding to Genes of the MHC on Chromosome 6 and the Short Arm of Chromosome 11.- HLA Typing on Single Human Hairs: DNA Probes to Enzymatically Amplified Genes.- Application of DNA Polymorphisms in Paternity Testing in Germany: Solution of an Incest Case Using Bacteriophage M13 Hybridization with Hypervariable Minisatellite DNA.- DNA: Postmortem Stability in Various Human Organ Tissues.- The Application of DNA-Print for Identification from Forensic Biological Materials.- Identification in Blood Stain Through DNA Typing with C4 and HLA-DR Probes (Abstract).- V. Stains.- Phylogeny and Ontogeny of Blood Group Antigens. A Study by Polychromatic Tissue Immunofluorescence of ABH and Related Antigens.- Typing of ABH Antigens in Body Fluids by a Two Dimensional Absorption-Inhibition Procedure.- Immunochemical Detection of ABH Antigens in Hairs.- Determination of ABH Antigens in Fingernails Using the APAAP (Immunoalkaline Phosphatase) Technique.- Absorption-Elution on Microplates (AEMP): An Improved Method for Identification of the ABH Major Glycoproteins in Saliva and Semen of Secretors.- Dot Blot ELISA on Nitrocellulose Membranes (NC): a New Method for Typing Lewis and ABO of Body Fluids (Saliva, Semen, Vaginal Secretions, Sweat and Urine).- Identification of Blood Group Substances of Fingerprints on the Murder Weapon by Means of the Adhesive Strip Method.- Interpretation of the ABH Reactions of Casework Seminal Stains.- Immunocytochemical ABH Blood Group Staining in Vaginal Swabs.- The Application of the Frozen Erythrocytes in the Bloodstain Diagnostic.- The Typing of ABH Antigens in Human Bone.- The Application of Immunoglobulin Allotyping in Forensic Stain Analysis; Reliability and Sensitivity of Gm and Km Typing.- Glm (f) Immunoblot Procedure.- Persistence of Gm Allotypes in Bloodstains Exposed to adverse Conditions.- An Approach to Individualisation of Micro-Bloodstains Using Immunochemophoresis.- Haptoglobin Subtyping in Bloodstains.- Sensitivity of a Micromethod for Haptoglobin Typing.- A Sensitive Method for Subtyping GC in Bloodstains.- Tf and Alpha-1-AT Typing in Bloodstains by Isoelectric Focusing.- Effects of Ultraviolet Irradiation on the Electrophoretical Typing of Serumprotein Polymorphisms.- Post Coital Changes in Semen Glyoxalase I (GLO).- PGM Subtyping of Semen and Vaginal Secretion.- DIA3-Typisierung an menschlichen Spermaproben, Spermaspuren, Zahnpulpen und Haarwurzeln mittels Isoelektrofokussierung.- P30 and Rape.- Zum Beweiswert des Schwangerschaftsnachweises an Blutspuren mittels fotometrischer Bestimmung der hitzestabilen alkalischen Phosphatase (hAP).- Bloodtyping in Human Dental Pulp by Immunoenzyme Techniques.- Simultaneous Typing of EsD and PGM1 Polymorphs in Dental Pulp (Abstract).- Mucosubstance and Lectin Histochemistry of Cervical Glands in Human Uteri.- Enzymdarstellung am fixierten Organgewebe.- VI. Population Genetics.- Population Genetics, a Short Introduction.- Population Genetics: Mathematical Problems (Abstract).- Practical Application of Population Genetics: The Genetic Survey “Provinces Francaises”.- Genetic Heterogeneity in Italy (Abstract).- The Polymorphism of Bf and C3 in the Population of Veneto (Italy).- Distribution of Gc, Pi and Tf Subtypes in Sardinia (Italy).- Alpha-2-HS-Glycoprotein Polymorphism in Tuscany (Italy).- Distribution of Genetically Determined Deficient Variants of Glucose-6-Phosphate Dehydrogenase (G6PD) in Southern Italy.- Polymorphisms of Alpha-1-Antitrypsin and Transferrin in NorthWest Germany.- Formal Genetics Studies on ALAD, AMY2, ESD, GLO1, HP, ORM and PGP Polymorphisms.- Blood Groups, Serum Proteins and Red Cell Isoenzymes - A Population Genetic Study on South Africa/Mocambique.- Studies on the Human Immunoglobulin Allotypes Among Han and Minority Nationalities in China.- A National Bank for Genetic Data of Disappeared Children in Argentina: Task up to 2050.- VII. Biostatistics.- Paternity Testing with an Absent Mother: The Probability of Exclusion of Red Cell Surface Antigen, Gm, Hp, and HLA Systems in North American Whites and Blacks.- A Protocol for Reporting Single Indirect Exclusions.- The Bias of the Dichotomy Exclusion/Non-Exclusion and the Evidential Value of L (or W).- The Avuncular Index and the Incest Index.- Vaterschaftsstatistik in Erbsystemen mit n kodominanten Allelen.- Ein Statistikpaket für die Abstammungsbegutachtung.- Empirical and Theoretical Studies on “Seroanalysis”.- Seroanalysis as a Means of Establishing a Child’s Unkown Putatively Alien Paternity.- Construction of Two Locus Haplotype HLA-A,B Matrices for Poorly Studied Populations.- On the Question of the Reliability of Silent Gene Frequencies Derived from Maximum-Likehood Estimates.- VIII. Varia.- Blood Group Determination in Stored Alcohol Containing Blood Samples for Identity Examination.- Blood Groups in Patients with Malignant Diseases.- Die Belastung des genetischen Materials im slowenischen Gebiet Zirovski VRH (Uranium Radioaktive Strahlung).- Rechtsvergleichende Darstellung der Vaterschaftsangelegenheiten in der SFR Jugoslawien mit besonderer Rücksicht auf die Reformbestrebungen in der SR Montenegro.