Advances in Anti-Inflammatory Drug Research

ISBN-13: 9783848498932 / Angielski / Miękka / 2012 / 72 str.

Atul Bhardwaj; Jatinder Kaur

Opis

This book is focused on the development of non-steroidal anti-inflammatory drugs (NSAIDs); the biological target of these drugs is cyclooxygenase (COX) enzyme, which exists in two closely related isoforms viz. COX-1and COX-2. Based on the housekeeping functions of COX-1isoform and pathophysiological roles COX-2 isoform, the selective inhibition of COX-2 is desirable. NSAIDs like aspirin, ibuprofen, indomethacin, diclofenac, celecoxib, rofecoxib etc. exert their anti-inflammatory effects through the selective/non-selective inhibition of COX-1and/or COX-2 enzymes.

O autorze

Dr. Atul Bhardwaj born in Punjab India and had his schooling in Batala. He obtained B.Sc. (Hons) and M.Sc. (Hons) in Chemistry followed by PhD. in Synthetic Organic & Medicinal Chemistry at G.N.D.U. Amritsar. He worked as Project Scientist at IIT Kanpur. Presently, working as Postdoctoral researcher (Drug discovery) at University of Alberta, Canada