Advanced Free Radical Reactions for Organic Synthesis

ISBN-13: 9780080443744 / Angielski / Twarda / 2004 / 270 str.

Hideo Togo

Opis

Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists.

• Introduces and reviews the use of radicals to perform synthetic transformations
• Practical details are provided for the most important methods
• Numerous references to the original literature

Recenzje

"The author has succeeded in presenting many facets of this very interesting area of chemistry in a highly engaging manner. As a result, anyone who wishes to familiarize themselves with the field of radical chemistry should take the time to look through Advanced Free Radical Reactions for Organic Synthesis." --ORGANIC CHEMISTRY, 2005

Spis treści

What are free radicals
Functional group conversion
Intramolecular radical cyclizations
Intermolecular radical addition reactions
Alkylation of aromatics
Intramolecular hydrogen-atom abstraction
Synthetic uses of free radicals for nucleosides and sugars: Barton-McCombie reaction
Barton decarboxylation reaction with N-hydroxy-2-thiopyridone
Free radical reactions with metal hydrides
Stereochemistry in free radical reactions
Free radicals related to biology
Free radicals for green chemistry