Activated Charcoal in Medical Applications

ISBN-13: 9780824793005 / Angielski / Twarda / 1995 / 608 str.

David O. Cooney;Cooney

Opis

This work highlights the great effectiveness of activated charcoal in treating drug overdoses and poisonings in both humans and animals. It brings together information from significant studies of the use of activated charcoal for medical purposes, describing all available charcoal products and their characteristics. The ability of activated charcoal to reduce the systemic absorption of an array of drugs, chemicals and biochemical substances, including analgesics, antipyretics, sedatives, alkaloids, snake venoms and bacterial and fungal toxins, is detailed.

Spis treści

Introduction

Historical Background of Activated Charcoal

Fundamentals of Activated Charcoal and the Adsorption Process

Properties of Antidotal Charcoal

The Nature of Drug Absorption, Distribution, and Elimination

Basic Details of Pharmacokinetic Modeling

Methods for Treating Poisoning and Drug Overdose

The Design of Clinical Studies and Data Treatment

Some Basic Aspects of Antidotal Charcoal

The Classic Studies of Andersen

Effects of Activated Charcoal on Major Classes of Drugs and Chemicals

Effect of Charcoal on Other Classes of Drugs

Effect of Administration Time, Food, and Gastric pH

Effect of Multiple Doses of Charcoal

Ipecac, Cathartics, and Charcoal: Interactions and Comparative Efficacies

The Development of Palatable Formulations

Hazards Associated with Antidotal Charcoal Use

Effect of Charcoal on Various Inorganic Substances

Effect of Charcoal on Endogenous Biochemicals

Use of Charcoal to Treat Poisoning in Animals

Reports from the Soviet Union

Resins and Clays as Sorbents

Other Medicinal Uses of Charcoal in Humans

Other Biochemical and Biological Uses of Charcoal

Summary

O autorze

Cooney, David O.