Chemistry and Biochemistry of the Amino Acids

ISBN-13: 9789401086424 / Angielski / Miękka / 2011 / 684 str.

Graham Barrett

Opis

Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.

Spis treści

Nomenclature of Amino Acids.- The Protein Amino Acids.- Beta and Higher Homologous Amino Acids.- The Non-Protein Amino Acids.- Metabolic and Pharmacological Studies.- The Biosynthesis of Amino Acids in Plants.- Enzyme Inhibition by Amino Acids and their Derivatives.- Synthesis of Amino Acids.- Protected Amino Acids in Peptide Synthesis.- Resolution of Amino Acids.- Reactions of Amino Acids.- Degradation of Amino Acids Accompanying in vitro Protein Hydrolysis.- Racemization of Amino Acids.- Ion-Exchange Separation of Amino Acids.- Liquid Chromatography of Amino Acids and their Derivatives.- Gas-Liquid Chromatographic Separation of Amino Acids and their Derivatives.- Mass Spectrometry of Amino Acids and their Derivatives.- Nuclear Magnetic Resonance Spectra of Amino Acids and their Derivatives.- The Optical Rotatory Dispersion and Circular Dichroism of Amino Acids and their Derivatives.- Colorimetric and Fluorimetric Detection of Amino Acids.- Physical Properties of Amino Acid Solutions.- X-Ray Crystal Structures of Amino Acids and Selected Derivatives.