Application of Gene Therapy in Dentistry

ISBN-13: 9783659529412 / Angielski / Miękka / 2014 / 64 str.

Rai Shalu;Dasgupta Subhankar;Misra Deepankar

Opis

Gene therapy comprises of introducing specific genetic material into target cells without producing toxic effects on surrounding tissue. Gene therapy is one of the recent advances in this field to deal with this obstacle with promising prospects. As an oral physician it is our responsibility to treat common oral premalignant lesions and conditions like leukoplakia and oral submucous fibrosis which have a definite malignant potential if timely and early diagnosis and treatment is not provided. Treatment options for recurrent or refractory oral cancers are limited. A Medline search was done including the international literature published between 1989 and 2013. It was restricted to English language articles and published work of past researchers including in vitro and in vivo studies. Google search on gene therapy was also done. Despite advances in surgery, radiotherapy, and chemotherapy, the survival of patients with oral squamous cell carcinoma has not significantly improved over the past several decades. A potential approach to the treatment of oral premalignant and malignant disorders is gene therapy.

O autorze

Dr. Shalu Rai is HOD of Oral Medicine and Radiology; Institute of Dental Studies and Technologies; Kadrabad, Modinagar. She had done her MDS in Oral Medicine and Radiology from G.D.C Nagpur. She is a teacher, mentor and councellor with highest and deepest commitment to excellence in undergraduate and postgraduate education for the past 16 years