Principles of Receptor Physiology

ISBN-13: 9783642650659 / Angielski / Miękka / 2011 / 600 str.

Werner R. Loewenstein

Opis

Why should there be a handbook of sensory physiology, and if so, why now' The editors have asked this question, marshalled all of the arguments that seemed to speak against their project, and then discovered that most of these arguments really spoke in favor of it: there seemed to be no doubt that the attempt should be made and that it should be made now. No complete overview of sensory physiology has been attempted since Bethe's "Handbuch der normalen und pathologischen Physiologie", nearly forty years ago. Since then, the field has evolved with unforeseen rapidity. Although electric probing of single peripheral nerve fibers was begun by ADRIAN and ZOTTERMAN as early as 1926, in the somatosensory system, and extended to single optic nerve fibers by HARTLINE in 1932, the real upsurge of such single-unit studies has only come during the last two decades. Single-cell electrophysiology has now been applied to all sensory modalities and on almost every conceivable phylogenetic level. It has begun to clarify peripheral receptor action and is adding to our. understanding of the central processing of sensory information. In parallel with these developments, there have been fundamental studies of the physics and chemistry of the receptors themselves: these studies are leading to insights into the mechanisms of energy transduction and nerve impulse initiation.

Spis treści

1 Mechano-Chemical Conversion.- 2 Proteins in Bioelectricity. Acetylcholine-Esterase and -Receptor.- 3 Transmission Action on Synaptic Neuronal Receptor Membranes.- 4 The General Electrophysiology of Input Membrane in Electrogenic Excitable Cells.- 5 Formation of Neuronal Connections in Sensory Systems.- 6 The Relation of Physiological and Psychological Aspects of Sensory Intensity.- 7 Sensory Power Functions and Neural Events.- 8 Generation of Responses in Receptor.- 9 Mechano-electric Transduction in the Pacinian Corpuscle. Initiation of Sensory Impulses in Mechanoreceptors.- 10 A Biophysical Analysis of Mechano-electrical Transduction.- 11 Responses of Nerve Fibers to Mechanical Forces.- 12 The Early Receptor Potential.- 13 The Nature of the Photoreceptor in Phototaxis.- 14 Sensory Transduction in Hair Cells.- 15 Transducer Properties and Integrative Mechanisms in the Frog’s Muscle Spindle.- 16 Static and Dynamic Behavior of the Stretch Receptor Organ of Crustacea.- 17 Patterns of Organization of Peripheral Sensory Receptors.- Author Index.