Lung Tumors: Lung, Mediastinum, Pleura, and Chest Wall

ISBN-13: 9783540169208 / Angielski / Miękka / 1988 / 272 str.

Barth Hoogstraten; Bruce J. Addis; Heine H. Hansen

Opis

This series on the treatment of cancer is sponsored by the UICe. The editors and authors feel strongly that more standar dization in cancer therapy is needed on a worldwide basis. This, of course, is only possible if experts from all countries subscribe to a joint policy of making their treatment designs available to practising oncologists all over the world. Current Treatment of Cancer discusses all the equipment and methods now in use in cancer therapy. It covers all types of cancer, thus providing the reader with comprehensive infor mation on cancer management. In recent decades there has been a tremendous improve ment in the treatment of cancer, and there is hope for even fur ther success in this fight. We are convinced that this series will help us to make a concerted response to the challenge of can cer. UICC Treatment and Rehabilitation Programme Ismail Elsebai Chairman Preface Part I Members of two institutions, the Brompton Hospital in London and the Finsen Institute in Copenhagen, were invited to write on lung cancer, and after reading the manuscripts it was decided that the contents of three pairs of chapters overlapped sufficiently for them to be combined."

Spis treści

I. Lung Tumors.- 1. Epidemiology.- Etiologic Considerations.- Trends in Tobacco Consumption.- Further Reading.- 2. Early Detection: Screening.- The Philadelphia Pulmonary Neoplasm Project.- The Mayo Lung Project.- Further Reading.- 3. Biology of Lung Cancer.- Growth Characteristics.- Chromosomal Studies.- In Vitro Clonogenic Assays.- Monoclonal Antibodies.- Heterotransplantation.- Tumor Markers.- Tumor Heterogeneity.- 4. Pathology of Lung Cancer.- Premalignant Change and Early Carcinoma.- Bronchial Papillomas and Papillary Carcinoma.- Squamous Cell (Epidermoid) Carcinoma.- Adenocarcinoma.- Adenosquamous Carcinoma.- Large Cell Undifferentiated Carcinoma.- Spindle-Cell Carcinoma and Carcinosarcoma.- Small Cell Carcinoma.- Tumors of Low-Grade Malignancy.- Further Reading.- 5. Histopathology, Ultrastructure, and Cytology.- WHO Classification.- Squamous Cell Carcinoma.- Small Cell Carcinoma.- Adenocarcinoma.- Large Cell Carcinoma.- Bronchial Carcinoids.- Mesothelioma.- Further Reading.- 6. Clinical Features.- Intrathoracic Symptoms.- Extrathoracic Metastatic Symptoms.- Paraneoplastic Manifestations.- 7. Diagnostic Procedures.- The Lung.- Radiology.- Conventional Tomography.- Other Radiological Techniques.- Sputum Cytology.- Bronchoscopy.- Transthoracic Lung Biopsy.- Pleura.- Pleural Fluid.- Mediastinum.- Invasive Techniques.- Mediastinoscopy.- Distant Metastases.- Detection of Liver Metastases.- Detection of Bone and Bone Marrow Metastases.- Detection of Central Nervous System Metastases.- Detection of Other Metastases.- 8. Staging.- T Stage.- N Stage.- Noninvasive Assessment of the Mediastinum.- M Stage.- Staging at Thoracotomy.- Autopsy Staging.- Relevance to Small Cell Lung Cancer.- References.- 9. Staging and Prognosis.- 10. Treatment at the Finsen Institute.- Treatment of Squamous Cell, Adeno-, and Large Cell Carcinoma.- Small Cell Carcinoma of the Lung.- Mesothelioma.- Further Reading.- 11. Surgical Treatment in Non-Small Cell Carcinoma of the Lung: The Memorial Sloan-Kettering Experience.- Occult Carcinomas of the Lung.- Treatment of T1 NO M0 and T2 N0 M0 Tumors.- Treatment of T1 N1 and T2 N1 Tumors.- Surgery in Patients with Advanced Disease.- Tumors Invading Chest Wall (T3).- Superior Sulcus Tumors.- Treatment of N2 MO Tumors.- Treatment of T3 Lesions Due to Proximity to Carina.- Conclusion.- References.- 12. Treatment at Brompton Hospital and Royal Marsden Hospital.- Pretreatment Preparation (by P. Goldstraw).- Surgery (by P.Goldstraw).- Adjuvant Therapy (by P.Goldstraw)..- Role of Radiotherapy (by J.R.Yarnold).- Chemotherapy (by S.G.Spiro).- Specific Problems in Inoperable Patients and Terminal Care (by S.G.Spiro).- 13. Prognosis and End Results.- Non-Small Cell Lung Cancer.- Natural History of Inoperable Disease.- Small Cell Lung Cancer.- Further Reading.- II. Tumors of the Mediastinum, Pleura, and Chest Wall.- 14. Pathology of Mediastinal Tumors.- Endocrine Tumors and Hyperplasias.- Tumors of the Thymus.- Tumors of Neural Origin.- Mediastinal Lymphadenopathy and Related Disorders.- Mediastinal Cysts.- Soft Tissue Tumors of the Mediastinum.- Mediastinal Fibrosis (Sclerosing Mediastinitis).- References.- 15. Pathology of Tumors of the Pleura and Chest Wall.- Pleural Tumors.- Tumors of the Chest Wall.- References.- 16. Primary Mediastinal Tumors.- Anatomical Boundaries.- Classification.- Symptoms and Signs.- Investigation.- Reference.- 17. Chest Wall Tumors.- Presenting Symptoms and Signs.- Investigation.- Surgical Management.- The Incision.- Resection.- Closure.- 18. Malignant Mesothelioma.- Epidemiology.- Pathology.- Clinical Features.- Diagnosis.- Treatment.- Prognosis.- Conclusions.- References.- 19. Radiotherapy of Mediastinal and Chest Wall Tumors.- Tumors of the Mediastinum.- Tumors of the Chest Wall and Pleura.- Radiation Techniques.- Radiation Dosage.- Further Reading.- 20. Chemotherapy of Mediastinal Tumors.- Hodgkin’s Disease.- Non-Hodgkin’s Lymphomas.- Germ Cell Tumors.- Thymomas.- Sarcomas.- Chemotherapy of Primary Malignant Chest Wall Tumors.- Management.