Hematologic Malignancies

ISBN-13: 9783540162933 / Angielski / Miękka / 1986 / 111 str.

Barth Hoogstraten; J. R. Durant; F. W. Gunz

Opis

This new series on the treatment of cancer is sponsored by the VICe. The editors and authors feel strongly that more standardiza tion is needed on a worldwide basis in cancer therapy. This, of course, is only possible if experts from all countries subscribe to a joint policy of making their treatment designs available to practising oncologists all over the world. Current Treatment of Cancer will discuss all the equipment and methods now in use in cancer therapy. It will cover all types of cancer, thus providing the reader with comprehensive information on cancer management. In recent decades there has been a tremendous improvement in the treatment of cancer, and there is hope for even further success in this fight. We are convinced that this series will help us to make a concerted response to the challenge of cancer. VICC Treatment and Rehabilitation Programme Ismail Elsebai Chairman VII Preface During the past two decades we have witnessed an exciting evolution in the un derstanding and management of hematologic malignancies. The number of drugs available 20 years ago for the treatment of acute leukemia was so small that the disease in children and in adults could be discussed within one chapter. Since then, rapid progress has been made in the management of childhood leukemia, making for a much better prognosis. Over the past 10 years we have seen the same developments in respect of leukemia in adults."

Spis treści

1. Treatment of Chronic Leukemias.- Chronic Myeloid Leukemia.- Clinical Picture.- Laboratory Investigations.- Management.- Prognosis.- Chronic Lymphocytic Leukemia.- Clinical Picture.- Laboratory Investigations.- Management.- Prognosis.- Further Reading.- 2. Acute Leukemia in Adults.- Diagnosis.- Preliminary Therapy.- Defects of Blood Cell Production.- Leukemic Cell Hyperproliferation.- Products of Leukemic Cells.- Concomitant Medical Problems.- Acute Lymphoblastic Leukemia.- Remission Induction.- Remission Maintenance.- Remission Reinduction.- Acute Myeloid Leukemia.- Remission Induction.- Treatment of Relapse.- Complications of Therapy.- Further Reading.- Editorial Comment.- 3. Myeloproliferative Disorders: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis/Agnogenic Myeloid Metaplasia.- Polycythemia Vera.- Epidemiology.- Symptoms and Signs.- The Spent Phase.- Differential Diagnosis.- Diagnostic Approach.- PVSG Criteria.- Prognosis.- Treatment.- Essential Thromboeythemia.- Epidemiology.- Symptoms and Signs.- Differential Diagnosis.- Diagnostic Approach.- PVSG Criteria.- Prognosis.- Treatment.- Idiopathic Myelofibrosis/Agnogenic Myeloid Metaplasia.- Epidemiology.- Symptoms and Signs.- Differential Diagnosis.- Diagnostic Approach.- Prognosis.- Treatment.- Further Reading.- 4. Hodgkin’s Disease.- Pathologic Clarification.- Pathogenesis and Staging.- Radiotherapy for Stages I-IIIA.- Chemotherapy for Stages ??? and IV.- Salvage Therapy.- Complications of Treatment.- Present Studies Testing Ideas for Improving Results.- Follow-up.- Summary.- Further Reading.- 5. Non-Hodgkin’s Lymphoma.- Pathology.- Low Grade Lymphomas.- Intermediate Grade Lymphomas.- High Grade Lymphomas.- Early Detection and Diagnosis.- Staging.- Treatment Planning.- Indolent Lymphomas.- Aggressive Lymphomas.- Pretreatment Preparation.- Surgery.- Radiotherapy.- Adjuvant Radiotherapy.- Palliative Radiotherapy.- Chemotherapy.- Drugs.- Drug Combinations.- Schedule.- Medical Complications of Lymphoma.- Prognosis and End Results.- Follow-up.- Further Reading.- 6. Multiple Myeloma.- Incidence.- Etiology and Pathogenesis.- Clinical Manifestations.- Bone Marrow.- Protein Abnormalities.- Skeletal Abnormalities.- Other Laboratory Manifestations.- Staging.- Treatment.- Single Drug Therapy.- Combination Chemotherapy.- Radiotherapy.- Immunotherapy.- Special Manifestations.- Further Reading.