Visual Transduction and Non-Visual Light Perception

ISBN-13: 9781588299574 / Angielski / Twarda / 2008 / 509 str.

Colin J. Barnstable

Opis

Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, The Visual Transduction Cascade: Basic and Clinical Principles reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths -- a good example of the limitations of the human sensory systems. Comprehensive and penetrating, The Visual Transduction Cascade: Basic and Clinical Principles brings together the developmental, structural, and molecular mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.

Spis treści

Evolution of the Visual System An Organ of Exquisite Perfection Ayoub G Photoreceptor Structure, Function and Development Development of the Foveal Specialization Bumsted O’Brien KM Contribution of Environmental Factors to Rod Photoreceptor Development Levine E and Fuhrmann S The Retinal Pigment Epithelium and the Visual Cycle Photoreceptor-RPE Interactions: Physiology and Molecular Mechanisms Finnemann SC, Chang Y Molecular Biology of IRBP and its Role in the Visual Cycle Borst DE, Boatright JH and Nickerson JM Visual Signaling in the Outer Retina Regulation of Photoresponses by Phosphorylation Gross AK, Wang Q, and Wensel TG The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of Photoreceptor Phosphodiesterase (PDE6) Cote RH Rhodopsin Structure, Function, and Involvement in Retinitis Pigmentosa Gleim S and Hwa J Multiple Signaling Pathways Govern Calcium Homeostasis In Photoreceptor Inner Segments Szikra T and Krizaj D The Transduction Channels of Rod and Cone Photoreceptors Tränkner D Rhodopsins in Drosophila Color Vision Jukam DM, Lidder P, Desplan C INAD Signalling Complex of Drosophila Photoreceptors Huber A and Meyer N.E. Visual Processing in the Inner Retina Visual Signal Processing in the Inner Retina Sagdullaev BT, Ichinose T, Eggers ED, and Lukasiewicz PD Color Vision and Adaptive processes Human cone spectral sensitivities and color vision deficiencies Stockman A and Sharpe LT Luminous Efficiency Functions Sharpe LT andStockman A Cone Pigments and Vision in the Mouse Jacobs GH Multifocal Oscillatory Potentials of the Human retina Kurtenbach A and Jaegle H Aging and Vision The Ageing of the Retina Bellmann C, Sahel J Ageing of the Retinal Pigment Epithelium Boulton ME Visual transduction and Age-related Changes in Lipofuscin Rozanowska M and Rozanowski B Non-Photoreceptor Light Detection and Circadian Rhythms A Non-Specific System Provides Non-Photic Information for the Biological Clock Lewandowski MH The Circadian clock: Physiology, genes and disease Antle M

Blurb

Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, Visual Transduction And Non-Visual Light Perception reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing readiation outside of the visible wavelengths -- a good example of the limitations of the human sensory systems. Comprehensive and penetrating, Visual Transduction And Non-Visual Light Perception brings together the developmental, structural, and molecular mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.