Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic...
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge con...
For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000 years ago, mentioned fees for eye surgery and penalties for unsuccessful operations that led to loss of the eye. Babylonian medicine was controlled by priests who directed the work of skilled surgeons. The earliest records of Egyptian medicine date from almost the same time. The Ebers Papyrus, dating back to more than 3500 years ago is a superbly preserved...
For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving...
The mechanisms of the various forms of glaucoma were unknown at the outset of the twentieth century. Late in the twentieth century, two nascent areas of research were beginning to provide glimpses of what the twenty-first century held in store for the future of glaucoma: the mechanisms of glaucomatous optic neuropathy and the molecular basis of the glaucomas. In Mechanisms of the Glaucomas: Disease Processes and Therapeutic Modalities, the authors review the most current knowledge available in the field and provide a basis in which researchers can effectively study the glaucomas. The...
The mechanisms of the various forms of glaucoma were unknown at the outset of the twentieth century. Late in the twentieth century, two nascent are...
Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, The Visual Transduction Cascade: Basic and Clinical Principles reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In...
Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spat...
The history of medicine has been substantially defined by a small number of monumental discoveries. Most of these breakthroughs have emerged from the biological sciences. One of the first great breakthroughs was the recognition by Koch in 1884 that pathogens could be transmitted from one living organism to another to cause disease. This profound concept led to a revolution in the approach to patient care that ultimately led to introduction of sterile techniques that greatly improved survivals of patients. This knowledge promoted the discovery of antibiotics 40 years later, which dramatically...
The history of medicine has been substantially defined by a small number of monumental discoveries. Most of these breakthroughs have emerged from the ...
Detection and responses to light are common features found throughout the plant and animal kingdoms. In most primitive life forms, a patch of light-sensitive cells make up a region containing a cell sheet devoid of any specialized anatomical structure. With the development of the eyes in more advanced life forms, light-sensing structures became more complex but primitive eyes are still in contiguity with other body tissues and fluids. The evolution of the eyeball promoted an increase in visual acuity and visual processing that, in turn, allowed vision to become the dominant sensory system for...
Detection and responses to light are common features found throughout the plant and animal kingdoms. In most primitive life forms, a patch of light-se...
An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvementis designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye. With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic...
An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvementis designed ...
