Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management

ISBN-13: 9781498799416 / Angielski / Twarda / 2018 / 684 str.

Vineet Kumar; Nandita Dasgupta; Shivendu Ranjan

Opis

The future of nanomaterials in electronics, mechanical, medical and various other industries depends up on how accurate are our nanotoxicity testing protocols and safety guidelines. This book focuses on causes and prevention of nanotoxicity induced by various nanoproducts. This book describes all these aspects of nanotoxicity critically in detail. This edited book contains five sections describing the basic principles, trends, challenges and future directions of nanotoxicity. Further, the limitations and challenges of current toxicity testing and future scope of toxicity testing of nanomaterials are discussed in detail.

Spis treści

Introduction to Nanotoxicity: Historical Overview of Nanotechnology in Context to Nanotoxicity. Nanomaterials and Environment. Safety Aspects of Nanomaterials Used in Foods, Drugs, Cosmetics and Other Iindustries. Ethics in Nanotechnology and Society Perception. Factors Affecting Toxicity of Nanomaterials: Impact of Physiochemical Properties and Surface Chemistry of Nanomaterials on Toxicity. Effect of Route of Nanomaterial Exposure on Toxicity of Nanomaterials. Effect of Test Dose on the Nanomaterials Toxicity. Influence of Test Model Selection on Nanotoxicity Evaluation. Nanotoxicity to Environment and Living Organism: Interaction of Nanomaterials with Biological Matrices. Toxic Effect of Nanomaterials to Environment. Interaction of Nanomaterials with Animal Cell Lines: in vitro Studies. Nanotoxicity Evaluation Using Experimental Animals: in vivo Studies. Influence of Nanomaterials on Human Health. Toxic Effect of Nanomaterials to Plants and Beneficial Soil Bacteria. Methods of Nanotoxicity Evaluation: Methods for in vitro and in vivo Animal Nanotoxicity Evaluation. In vitro and in vivo Nanotoxicity Evaluation in Plants. Nanotoxicological Evaluation in Water and Marine Organisms. Pharmacokinetics Approach for Nanotoxicity Evaluation. Genomic Approach in Nanotoxicity Evaluation. In silico Methods for Nanotoxicity Evaluation. Sensors for Toxicity Evaluation of Nanomaterials. Regulatory Guidelines and Future Risk Assessment Strategies in Nanotoxicity: Guidelines and Protocols for Nanotoxicity Evaluation. Regulations for Safety Assessment of Nanomaterials. Minimizing Nanotoxicity with Green Chemistry. Improving Nanotoxicity Evaluation Via the Use of miRNA, siRNA and Stem Cell Studies. Challenges, Recommendations and Strategies for Nanotoxicity Evaluation and its Management.

O autorze

Vineet Kumar is currently working as Dr DSK postdoctoral fellow in the Department of Chemistry, Panjab University Chandigarh, UT India. He has worked in different areas of biotechnology and nanotechnology in various institutes and universities namely, CSIR-Institute of Microbial Technology, Chandigarh, U.T., India, CSIR-Institute of Himalayan Bioresource Technology, Palampur, H.P. India and Himachal Pradesh University, Shimla, H.P. India.
His areas of interest include green synthesis of nanoparticles, nanotoxicity testing of nanoparticles and application of nanoparticles in drug delivery, food technology, sensing, dye degradation and catalysis. He has published many research articles in these areas featuring in peer-reviewed journals.

Nandita Dasgupta is currently serving as Research Associate at VIT University, Vellore, Tamil Nadu, India. She has exposure of research institutes and industries including CSIR-Central Food Technological Research Institute, Mysore, India and Uttar Pradesh Drugs and Pharmaceutical Co. Ltd., Lucknow, India. Her areas of interest include toxicological analysis, natural products technology, nanobiotechnology and agri-food technology. She has published many scientific articles in international peer reviewed journals and also serving as editorial board member and referee for reputed international peer reviewed journals. She has received Elsevier Certificate for “Outstanding Contribution” in Reviewing from Elsevier, The Netherlands. She has also been nominated for Elsevier advisory panel for Elsevier, The Netherlands. She was the Guest Editor in Journal of Chemistry for the special issue entitled “Food Nanotechnology Opportunities and Challenges”.

Shivendu Ranjan is currently working as DBT-Research Fellow, Department of Biotechnology, Ministry of Science and Technology, Govt of India at VIT University, Vellore, Tamil Nadu, India. He is also serving for a non-government organization as an Honorary-Director, Research Wing, Veer Kunwar Singh Memorial Trust, Chapra, Bihar, India. He is the Founder-Director at Xpert Arena Technological Services Pvt. Ltd., India (www.xpertarena.com); this company is dedicated to serve in online and offline sectors with a vision to simplify the education. He has also founded and drafted the concept for first edition of “VIT Bio Summit” in 2012 and the same has been continued till date by the university.  His area of research is multidisciplinary which are as but not limited to: Nano-food technology, Nano-agri technology, Nanobiotechnology, Nano-toxicology, Natural products technology, Natural products chemistry, Bio-business, Food chemistry and Food Engineering. He has published many scientific articles in international peer reviewed journals and also serving as editorial board member and referee for reputed international peer reviewed journals.