Toxins and Biologically Active Compounds from Microalgae, Volume 2: Biological Effects and Risk Management

ISBN-13: 9781482231465 / Angielski / Twarda / 2014 / 700 str.

Gian Paolo Rossini

Opis

Toxins and Biologically Active Compounds from Microalgae: Volume 2: Biological Effects and Risk Management is devoted to the effects toxic microalgae and their poisonous products exert on living systems and how they may affect human activities. The most advanced information regarding the molecular mechanisms of action of major groups of toxins is presented, to frame for the description of toxic responses found in living systems exposed to microalgal toxins. Accounts of the recognized environmental effects of harmful algal blooms and the existing therapeutic applications of some toxins have been included. The picture is completed by the description of current initiatives to manage the risks posed by toxic microalgae, including strategies for the detoxification of contaminated seafood and the efforts to use most advanced informatic tools for the development of models for robust predictions regarding the appearance and the dynamics of harmful algal blooms.The complexity of risk management in the field is presented from a global perspective by highlighting major issues approached in world regions whose economic importance with regard to the production and commercialization of seafood is undeniable.

Spis treści

Toxic microalgae and cyanobacteria. Harmful algae and their toxins: progress, paradoxes and paradigm shifts. Micro‐algal and cyanobacterial producers of biotoxins. Detection and identification of toxic microalgae by the use of innovative molecular methodologies. Factors affecting algal toxicity. Microalgal toxins: chemistry and detection. Chemistry and detection of okadaic acid/dinophysistoxins, pectenotoxins and yessotoxins. Chemistry of brevetoxins. The chemistry of ciguatoxins: from the first records to current challenges of monitoring programs. Palytoxins: chemistry and detection. Chemistry and detection of domoic acid and isomers. Current knowledge of paralytic shellfish toxin biosynthesis, molecular detection and evolution. Current understanding and hypotheses on the biosynthesis of microalgal polyether toxins. Total synthesis of marine polycyclic ether natural products. Instrumental methods for determination of marine microalgal toxins. Biological assays for toxin detection: characteristics, potential and critical issues. Marine toxin detection methods in regulation – from validation to implementation.

O autorze

Gian Paolo Rossini