Antiangiogenic Cancer Therapy

ISBN-13: 9780849327995 / Angielski / Twarda / 2007 / 841 str.

Darren W. Davis; Roy S. Herbst; James L. Abbruzzese

Opis

Anti-Angiogenic Cancer Therapy provides information on the process of angiogenesis and its role in tumor growth and metastasis. This book examines angiogenesis inhibitors under clinical investigation as well as early agents used in preclinical studies. It discusses the unique aspects of targeting and inhibiting angiogenesis and the challenges associated with clinical development of angiogenesis including trial design and surrogate marker endpoints. With information on the design and execution of preclinical studies, the application of genomics and angiogenesis, and the regulatory approval process, this text is ideal for pharmaceutical scientists, pharmacologists, and oncologists.

Spis treści

Angiogenesis in Cancer; Targeting Angiogenesis for Cancer Therapy; Translating Angiogenesis Inhibitors to the Clinic;  Treatment of Specific Cancers with Angiogenesis Inhibitors

O autorze

Darren W. Davis, Roy S. Herbst, James L. Abbruzzese